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首页> 外文期刊>Emerging Infectious Diseases >Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015
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Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015

机译：2013年至2015年，中国在3次主要流行浪潮中对人的甲型H7N9流感病毒感染

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摘要

Since March 2013, a novel influenza A(H7N9) virus has caused 3 epidemic waves of human infection in mainland China. We analyzed data from patients with laboratory-confirmed influenza A(H7N9) virus infection to estimate the risks for severe outcomes after hospitalization across the 3 waves. We found that hospitalized patients with confirmed infections in waves 2 and 3 were younger and more likely to be residing in small cities and rural areas than were patients in wave 1; they also had a higher risk for death, after adjustment for age and underlying medical conditions. Risk for death among hospitalized patients during waves 2 and 3 was lower in Jiangxi and Fujian Provinces than in eastern and southern provinces. The variation in risk for death among hospitalized case-patients in different areas across 3 epidemic waves might be associated with differences in case ascertainment, changes in clinical management, or virus genetic diversity.
机译：自2013年3月以来，一种新型的甲型H7N9流感病毒在中国大陆引起了3次人类感染流行病。我们分析了来自实验室确诊的甲型H7N9流感病毒感染患者的数据，以估计在3次浪潮中住院后严重后果的风险。我们发现，与第1浪患者相比，在第2浪和第3浪中已确诊感染的住院患者更年轻，更可能居住在小城市和农村地区。在调整年龄和基本医疗条件之后，他们的死亡风险也更高。在江西省和福建省，在第二，三波期间住院患者的死亡风险低于东部和南部省份。在三个流行病波中，不同地区住院病例患者的死亡风险差异可能与病例确定，临床管理变化或病毒遗传多样性的差异有关。

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