...
首页> 外文期刊>Emerging Infectious Diseases >Rotavirus Epidemiology in Bangui, Central African Republic, 2008 (http://wwwnc.cdc.gov/eid/article/20/7/13-1839)
【24h】

Rotavirus Epidemiology in Bangui, Central African Republic, 2008 (http://wwwnc.cdc.gov/eid/article/20/7/13-1839)

机译:2008年中非共和国班吉的轮状病毒流行病学(http://wwwnc.cdc.gov/eid/article/20/7/13-1839)

获取原文
           

摘要

To the Editor: Infection with group A rotavirus is among the leading causes of gastroenteritis in children, especially in sub-Saharan Africa (1). Data with regard to the incidence of rotavirus-A disease in the Central African Republic are limited (2). To estimate the prevalence of rotavirus-A disease among young children before introduction of rotavirus-A vaccine in Bangui, the capital of the Central African Republic, we performed a prospective study during February– September 2008. The target sample size, based on an expected 20% prevalence of rotavirus diarrhea and a 5% significance level, was 250 cases. All patients were children 0–5 years of age, who were hospitalized for acute diarrhea at the Complexe Pédiatrique, Bangui, the main hospital for children in the Central African Republic, and all had an illness that met the World Health Organization definition of a suspected case of rotavirus-A gastroenteritis (http://www.who.intuvi/ surveillance/RV_Case_Defs.pdf). After informed consent and epidemiologic and clinical data had been obtained, a fecal specimen was collected from each child. Samples were transported to the Institut Pasteur de Bangui, where they were tested for rotavirus- A antigen by using the VIKIA Rota-Adeno test, (VIKIA Rota-Adeno; bioMérieux SA, Lyon, France). Results were immediately reported to the referring physician.
机译:致编者:轮状病毒A感染是儿童肠胃炎的主要原因,尤其是在撒哈拉以南非洲地区(1)。关于中非共和国轮状病毒A病发病率的数据有限(2)。为了估算在中非共和国首都班吉市引入轮状病毒A疫苗之前幼儿中轮状病毒A疾病的患病率,我们在2008年2月至9月间进行了一项前瞻性研究。目标样本量基于预期轮状病毒腹泻的患病率为20%,显着水平为5%,为250例。所有患者均为0-5岁的儿童,他们因中非共和国儿童主要医院班吉的复杂腹泻而因急性腹泻而住院,并且所有疾病均符合世界卫生组织对可疑人群的定义。轮状病毒A型肠胃炎病例(http://www.who.intuvi/environmental/RV_Case_Defs.pdf)。获得知情同意并获得流行病学和临床数据后,从每个儿童中收集粪便标本。将样品运送到班吉巴斯德研究所,通过VIKIA Rota-Adeno测试(VIKIA Rota-Adeno;BioMérieuxSA,法国里昂)对轮状病毒A抗原进行检测。结果立即报告给转诊医师。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号