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首页> 外文期刊>Emerging Infectious Diseases >Susceptibility of Carrion Crows to Experimental Infection with Lineage 1 and 2 West Nile Viruses
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Susceptibility of Carrion Crows to Experimental Infection with Lineage 1 and 2 West Nile Viruses

机译：腐肉乌鸦对世系1和2西尼罗河病毒的实验感染的敏感性

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West Nile virus (WNV) outbreaks in North America have been characterized by substantial die-offs of American crows (Corvus brachyrhynchos). In contrast, a low incidence of bird deaths has been observed during WNV epidemic activity in Europe. To examine the susceptibility of the western European counterpart of American crows, we inoculated carrion crows (Corvus corone) with WNV strains isolated in Greece (Gr-10), Italy (FIN and Ita09), and Hungary (578/10) and with the highly virulent North American genotype strain (NY99). We also inoculated American crows with a selection of these strains to examine the strains’ virulence in a highly susceptible bird species. Infection with all strains, except WNV FIN, resulted in high rates of death and high-level viremia in both bird species and virus dissemination to several organs. These results suggest that carrion crows are highly susceptible to WNV and may potentially be useful as part of dead bird surveillance for early warning of WNV activity in Europe.
机译：北美西尼罗河病毒（WNV）爆发的特征是美国乌鸦（Corvus brachyrhynchos）大量死亡。相反，在欧洲WNV流行期间观察到鸟类死亡的发生率较低。为了检查西欧美洲乌鸦的易感性，我们用在希腊（Gr-10），意大利（FIN和Ita09）和匈牙利（578/10）分离的WNV株接种了腐肉乌鸦（Corvus corone）。高毒力北美基因型菌株（NY99）。我们还向美国乌鸦接种了这些菌株，以检查它们在高易感鸟类中的毒力。除WNV FIN外，所有菌株的感染均导致禽类的高死亡率和高水平病毒血症，并且病毒传播到多个器官。这些结果表明，腐肉乌鸦高度易受WNV感染，并且可能在欧洲进行WNV活动预警的死鸟监视中有用。

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