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首页> 外文期刊>Emerging Infectious Diseases >Multidrug-Resistant Corynebacterium striatum Associated with Increased Use of Parenteral Antimicrobial Drugs
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Multidrug-Resistant Corynebacterium striatum Associated with Increased Use of Parenteral Antimicrobial Drugs

机译：耐多药纹状体棒状杆菌与肠胃外抗菌药物使用增加有关

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Corynebacterium striatum is an emerging multidrug-resistant bacteria. We retrospectively identified 179 isolates in a clinical database. Clinical relevance, in vitro susceptibility, and length of parenteral antimicrobial drug use were obtained from patient records. For patients with hardware- or device-associated infections, those with C. striatum infections were matched with patients infected with coagulase-negative staphylococci for case–control analysis. A total of 87 (71%) of 121 isolates were resistant to all oral antimicrobial drugs tested, including penicillin, tetracycline, clindamycin, erythromycin, and ciprofloxacin. When isolated from hardware or devices, C. striatum was pathogenic in 38 (87%) of 44 cases. Patients with hardware-associated C. striatum infections received parenteral antimicrobial drugs longer than patients with hardware-associated coagulase-negative staphylococci infections (mean ± SD 69 ± 5 days vs. 25 ± 4 days; p
机译：纹状棒状杆菌是一种新兴的耐多药细菌。我们回顾性鉴定了临床数据库中的179个分离株。从患者记录中获得临床相关性，体外药敏性和肠胃外抗菌药物使用时间。对于硬件或设备相关感染的患者，将纹状体梭状芽孢杆菌感染的患者与凝固酶阴性葡萄球菌感染的患者进行匹配，以进行病例对照分析。总共121个菌株中有87个（71％）对所有经测试的口服抗菌药物均具有耐药性，包括青霉素，四环素，克林霉素，红霉素和环丙沙星。与硬件或设备隔离时，纹状体梭状芽胞杆菌在44例病例中有38例（87％）是致病性的。硬件相关性纹状体感染的患者接受肠胃外抗菌药物的时间比硬件相关性凝固酶阴性葡萄球菌感染的患者更长（平均±SD 69±5天vs. 25±4天; p

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