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首页> 外文期刊>Emerging Infectious Diseases >Transmission of Babesia microti Parasites by Solid Organ Transplantation
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Transmission of Babesia microti Parasites by Solid Organ Transplantation

机译：固体器官移植对小巴贝虫寄生虫的传播

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Babesia microti , an intraerythrocytic parasite, is tickborne in nature. In contrast to transmission by blood transfusion, which has been well documented, transmission associated with solid organ transplantation has not been reported. We describe parasitologically confirmed cases of babesiosis diagnosed ≈8 weeks posttransplantation in 2 recipients of renal allografts from an organ donor who was multiply transfused on the day he died from traumatic injuries. The organ donor and recipients had no identified risk factors for tickborne infection. Antibodies against B. microti parasites were not detected by serologic testing of archived pretransplant specimens. However, 1 of the organ donor’s blood donors was seropositive when tested postdonation and had risk factors for tick exposure. The organ donor probably served as a conduit of Babesia parasites from the seropositive blood donor to both kidney recipients. Babesiosis should be included in the differential diagnosis of unexplained fever and hemolytic anemia after blood transfusion or organ transplantation.
机译：微小红细胞巴贝氏体，一种红细胞内的寄生虫，在自然界中传播。与已有大量文献报道的输血传播相反，与实体器官移植有关的传播尚未见报道。我们描述了在寄生虫学上证实的约2例移植后≈8周被诊断为贝贝病的病例，其中有2名来自器官供体的肾脏同种异体移植受者在其因外伤死亡的那天被多次输血。器官供体和受体均未发现tick传感染的危险因素。通过存档的移植前标本的血清学检测未检测到针对小肠双歧杆菌寄生虫的抗体。但是，在捐献后进行测试时，有1个器官捐献者的献血者血清反应阳性，并且有tick暴露的危险因素。器官供体可能是巴贝虫寄生虫从血清阳性供血者到两个肾脏接受者的管道。在输血或器官移植后原因不明的发烧和溶血性贫血的鉴别诊断中应包括婴儿病。

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