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首页> 外文期刊>Emerging Infectious Diseases >Hantavirus Pulmonary Syndrome—The 25th Anniversary of the Four Corners Outbreak
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Hantavirus Pulmonary Syndrome—The 25th Anniversary of the Four Corners Outbreak

机译：汉坦病毒性肺综合症—四角爆发25周年

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During the spring of 1993, a mysterious respiratory disease struck the Four Corners region of the southwestern United States. Persons who became ill were generally young and previously healthy before succumbing to an acute febrile illness that began with simple influenza-like symptoms and often culminated in death by pulmonary edema and cardiovascular collapse. With astonishing speed and efficiency, a collaborative team of federal, state, and local healthcare workers, including clinicians, epidemiologists, and laboratory scientists, identified a newly discovered species of hantavirus as the causative agent of the outbreak. In the ensuing 25 years, the epidemiology, virology, pathophysiology, clinical course, and treatment of hantavirus pulmonary syndrome have been the focus of ongoing research. Because of its rarity, and because of the need for early acute intervention in the face of precipitous decline, recognition of the unique laboratory profile of hantavirus pulmonary syndrome in the setting of a predisposing exposure history is of paramount importance.
机译：在1993年春季，美国西南部的四个角落地区发生了一次神秘的呼吸道疾病。患病的人通常很年轻，以前很健康，然后死于急性发热病，这种疾病始于简单的流感样症状，常常因肺水肿和心血管衰竭而死亡。由联邦，州和地方医护人员组成的团队（包括临床医生，流行病学家和实验室科学家）以惊人的速度和效率，确定了新发现的汉坦病毒物种作为爆发的病原体。在随后的25年中，汉坦病毒肺综合征的流行病学，病毒学，病理生理学，临床过程和治疗一直是正在进行的研究重点。由于它的稀有性，并且由于面对急剧下降的情况需要进行早期急性干预，因此在易感性接触史的背景下认识到汉坦病毒性肺综合征的独特实验室特征至关重要。

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