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首页> 外文期刊>Frontiers in Psychology >Fear-Potentiated Startle and Fear Extinction in a Sample of Undergraduate Women Exposed to a Campus Mass Shooting
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Fear-Potentiated Startle and Fear Extinction in a Sample of Undergraduate Women Exposed to a Campus Mass Shooting

机译:暴露于校园大规模枪击事件的女大学生样本中恐惧恐惧惊吓和恐惧消灭

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Posttraumatic stress disorder (PTSD) is a common psychological disorder that affects a substantial minority of individuals. Previous research has suggested that PTSD can be partially explained as a disorder of impaired fear inhibition. The current study utilized a previously validated fear acquisition and extinction paradigm in a sample of 75 undergraduate women who were exposed to a campus mass shooting that occurred in 2008. We used a protocol in which conditioned fear was first acquired through the presentation of one colored shape (reinforced conditioned stimulus, CS+) that was paired with an aversive airblast to the larynx (unconditioned stimulus, US) and a different colored shape that was not paired with the airblast (non-reinforced conditioned stimulus, CS-). Fear was extinguished 10 min later through repeated presentations of the CSs without reinforcement. Number of clinically significant posttraumatic stress symptoms (PTSS) immediately following the mass shooting were positively associated with fear-potentiated startle (FPS) to the CS+ and CS- during late periods of acquisition. During early periods of fear extinction, PTSS was positively associated with FPS to the CS+. Results from the current study suggest that PTSS is related to altered fear inhibition and extinction during an FPS paradigm. In line with similar research, women with greater PTSS demonstrated a greater “fear load,” suggesting that these women experienced elevated fear to the CS+ during extinction after conditioned fear was acquired.
机译:创伤后应激障碍(PTSD)是一种常见的心理疾病,会影响少数人。先前的研究表明,PTSD可以部分解释为恐惧抑制功能障碍。当前的研究使用了先前验证过的恐惧获取和消灭范例,该样本来自75位2008年发生校园校园大规模枪击事件的女大学生。我们使用了一种协议,其中首先通过呈现一种彩色形状来获得条件性恐惧(增强型条件刺激,CS +)与厌恶性气枪配对至喉部(无条件刺激,US),而另一种有色形状与气枪不配对(非增强型条件刺激,CS-)。恐惧在10分钟后通过反复演示CS而没有消除而消失。大规模枪击事件发生后立即具有临床意义的重大创伤后应激反应症状(PTSS)与患者后期获得CS +和CS-的恐惧增强惊吓(FPS)正相关。在恐惧消退的早期,PTSS与FPS与CS +正相关。当前研究的结果表明,在FPS范例中,PTSS与恐惧抑制的改变和灭绝有关。与类似的研究一致,PTSS较高的妇女表现出更大的“恐惧负荷”,这表明这些妇女在获得条件性恐惧后的灭绝过程中对CS +的恐惧增强。

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