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Phosphorylation of histones in cells treated with hypertonic and acidic media.

机译:高渗和酸性介质处理过的细胞中组蛋白的磷酸化。

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Factors in the extracellular environment, specifically hypertonic or acidic growth media, are shown to alter the modification of histones in several cell lines. For histone 2A, changes in modification were visible in the mass pattern and were found to be primarily changes in phosphorylation. The increased modification of the core histones was quickly reversed when cells were returned to normal medium.
机译:细胞外环境中的因素,特别是高渗或酸性生长培养基,已显示出可改变几种细胞系中组蛋白的修饰。对于组蛋白2A,修饰的改变在质量模式中可见,并且发现主要是磷酸化的改变。当细胞返回正常培养基时,核心组蛋白的修饰增加迅速被逆转。

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