...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Molecular and Cellular Biology >The Caenorhabditis elegans vitellogenin gene family includes a gene encoding a distantly related protein.
【24h】

The Caenorhabditis elegans vitellogenin gene family includes a gene encoding a distantly related protein.

机译：秀丽隐杆线虫卵黄蛋白原基因家族包括编码远缘相关蛋白的基因。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

While the nematode Caenorhabditis elegans is more primitive than most egg-laying organisms, it's vitellogenins, or yolk protein precursors, appear to be more complex. C. elegans oocytes accumulate two major classes of yolk proteins. The first consists of two polypeptides with an Mr of about 170,000 (yp170A and yp170B) encoded by a family of five closely related genes called vit-1 through vit-5. The second class consists of two smaller proteins with Mr values of 115,000 (yp115) and 88,000 (yp88) which are cut from a single precursor. Here we report the cloning and analysis of a single-copy gene (vit-6) that encodes this precursor. The lengths of the gene and its mRNA are about 5 X 10(3) base pairs. Like vit-1 through vit-5, vit-6 is expressed exclusively in adult hermaphrodites. Comparison of portions of the coding sequence indicates that vit-6 is distantly related to the vit-1 through vit-5 gene family. Thus, even though the two classes of yolk proteins are antigenically and physically distinct, they are encoded by a single highly diverged gene family.
机译：尽管线虫秀丽隐杆线虫比大多数产卵生物原始得多，但其卵黄蛋白原或卵黄蛋白前体似乎更复杂。秀丽隐杆线虫卵母细胞积累两大类卵黄蛋白。第一个由两个多肽组成，Mr约为170,000（yp170A和yp170B），由五个紧密相关的基因家族（称为vit-1至vit-5）编码。第二类由两个较小的蛋白质组成，这些蛋白质的Mr值分别为115,000（yp115）和88,000（yp88），它们是从单个前体切下的。在这里，我们报告克隆和编码该前体的单拷贝基因（vit-6）的分析。该基因及其mRNA的长度约为5 X 10（3）个碱基对。像vit-1到vit-5一样，vit-6仅在成年雌雄同体中表达。编码序列各部分的比较表明，vit-6至通过vit-5基因家族与vit-1密切相关。因此，即使这两类蛋黄在抗原和物理上是不同的，它们也由一个高度不同的基因家族编码。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号