Growth factor-deprived BALB/c 3T3 murine fibroblasts can enter the S phase after induction of c-myc gene expression.

F Cavalieri; M Goldfarb

首页> 外文期刊>Molecular and Cellular Biology >Growth factor-deprived BALB/c 3T3 murine fibroblasts can enter the S phase after induction of c-myc gene expression.

【24h】

Growth factor-deprived BALB/c 3T3 murine fibroblasts can enter the S phase after induction of c-myc gene expression.

机译：缺乏生长因子的BALB / c 3T3鼠成纤维细胞可在诱导c-myc基因表达后进入S期。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Induction of quiescent BALB/c 3T3 murine fibroblasts by platelet-derived growth factor (PDGF) or fibroblast growth factor (FGFs) is accompanied by induction of c-myc gene expression. To study the role of c-myc in cell growth, we transfected BALB/c 3T3 cells with a plasmid construct containing a glucocorticoid-inducible c-myc gene. When these transfected cells were growth arrested in PDGF-FGF-freedefined medium, glucocorticoid treatment induced S-phase DNA synthesis. This induction of DNA synthesis was inefficient, and cell proliferation was not evident, suggesting that growth factors act through stimulation of c-myc expression together with other intracellular events.

机译：血小板衍生生长因子（PDGF）或成纤维细胞生长因子（FGFs）诱导静止的BALB / c 3T3鼠成纤维细胞伴随c-myc基因表达的诱导。为了研究c-myc在细胞生长中的作用，我们用含有糖皮质激素诱导的c-myc基因的质粒构建体转染了BALB / c 3T3细胞。当这些转染的细胞在无PDGF-FGF的特定培养基中生长停滞时，糖皮质激素治疗诱导S期DNA合成。 DNA合成的这种诱导是无效的，并且细胞增殖也不明显，表明生长因子通过刺激c-myc表达以及其他细胞内事件起作用。

著录项

来源
《Molecular and Cellular Biology》 |1987年第10期|共7页
作者
F Cavalieri; M Goldfarb;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词

相似文献

外文文献
中文文献
专利

1. Murine mRNA for the β‐subunit of integrin is increased in BALB/c‐3T3 cells entering the G1 phase from the G0 state [J] . Tominaga Shin-ichi FEBS Letters . 1988,第2期

机译：在从G0状态进入G1期的BALB / c-3T3细胞中，整合素β亚基的小鼠mRNA升高
2. Suppressive effects of chlorophyllin on mutagen-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002) and tumor promoter-dependent ornithine decarboxylase induction in BALB/c 3T3 fibroblast cells. [J] . Okai Y, Higashi Okai K, Yano Y, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 1996,第1期

机译：叶绿素对鼠伤寒沙门氏菌（TA 1535 / pSK 1002）中诱变剂诱导的umu C基因表达的抑制作用以及BALB / c 3T3成纤维细胞中依赖肿瘤启动子的鸟氨酸脱羧酶的诱导作用。
3. A growth factor-responsive gene of murine BALB/c 3T3 cells encodes a protein homologous to human tissue factor. [J] . S Hartzell, K Ryder, A Lanahan, Molecular and Cellular Biology . 1989,第6期

机译：鼠BALB / c 3T3细胞的生长因子响应基因编码与人类组织因子同源的蛋白质。
4. Growth Inhibition of Balb 3T3 Cells by Organotin Pyrimidine Polymers [C] . Deborah Siegmann-Louda, Charles E. Carraher Jr., Odette Gordon PMSE Symposia . 2005

机译：通过有机锡嘧啶聚合物的BALB 3T3细胞的生长抑制
5. Biocompatibility of electrospun polymer nanofibers (EPNs) with NIH 3T3 cell line and interaction of quercetin with different flavonoids: Induction of phase II enzymes in vitro cancer cell lines [D] . Benavides, Brenda S. 2011

机译：电纺聚合物纳米纤维（EPN）与NIH 3T3细胞系的生物相容性以及槲皮素与不同类黄酮的相互作用：体外癌细胞系中II期酶的诱导
6. Growth factor-deprived BALB/c 3T3 murine fibroblasts can enter the S phase after induction of c-myc gene expression. [O] . F Cavalieri, M Goldfarb 1987

机译：缺乏生长因子的BALB / c 3T3鼠成纤维细胞可在诱导c-myc基因表达后进入S期。
7. Growth factor-deprived BALB/c 3T3 murine fibroblasts can enter the S phase after induction of c-myc gene expression. [O] . Cavalieri, F, Goldfarb, M 1987

机译：缺乏生长因子的BALB / c 3T3鼠成纤维细胞可在诱导c-myc基因表达后进入S期。
8. In Situ Electron Microscopy of Cell Monolayers: Application to the Study of the Interactions Between Balb 3T3 Fibroblasts [R] . Collins T.R 1979

机译：细胞单层的原位电子显微镜检查：应用于Balb 3T3成纤维细胞间相互作用的研究

Growth factor-deprived BALB/c 3T3 murine fibroblasts can enter the S phase after induction of c-myc gene expression.

摘要

著录项

相似文献

相关主题

期刊订阅