Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines.

E Brownell; B Mathieson; H A Young; J Keller; J N Ihle; N R Rice

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Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines.

机译：检测小鼠造血组织，分离的淋巴细胞群和细胞系中的c-rel相关转录本。

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A portion of the human cellular homolog of v-rel, the transforming gene of the leukemogenic retrovirus reticuloendotheliosis virus, strain T, was used to survey RNAs from several mouse tissues, selected lymphocyte populations, and hematopoietic cell lines for c-rel expression. Relatively high levels of a high-molecular-weight transcript were observed in peripheral B and T cells, whereas lower levels were detectable in functionally immature thymocytes. These results suggested that, unlike c-myb and c-ets, the c-rel proto-oncogene plays a role in later stages of lymphocyte differentiation.

机译：人类细胞同源物v-rel的一部分，是白血病致病性逆转录病毒网状内皮病病毒T株的转化基因，用于调查几种小鼠组织，选定的淋巴细胞群和造血细胞系中的RNA，以表达c-rel。在外周B细胞和T细胞中观察到相对高水平的高分子量转录物，而在功能不成熟的胸腺细胞中可检测到较低水平。这些结果表明，与c-myb和c-ets不同，c-rel原癌基因在淋巴细胞分化的后期发挥作用。

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《Molecular and Cellular Biology》 |1987年第3期|共6页
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E Brownell; B Mathieson; H A Young; J Keller; J N Ihle; N R Rice;
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中图分类细胞生物学;
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2. Detection of low-abundant novel transcripts in mouse hematopoietic stem cells [J] . Hyeng-Soo Kim, Junmo Hwang, Young-Hun Kim, Molecular Genetics and Genomics . 2009,第4期

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3. Expression of heavy-chain constant region of immunoglobulin and T-cell receptor gene transcripts in human non-hematopoietic tumor cell lines. [J] . Kimoto Y Genes, Chromosomes and Cancer . 1998,第1期

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5. The effect of interleukin-7 and C-Kit signaling throughout the ontogeny of naive CD4+ lymphocytes from hematopoietic stem cells to maturity. [D] . Dudl, Eric Preston. 2006

机译：白细胞介素7和C-Kit信号传导在从造血干细胞到成熟的幼稚CD4 +淋巴细胞整个个体发育中的作用。
6. Detection of c-rel-related transcripts in mouse hematopoietic tissues fractionated lymphocyte populations and cell lines. [O] . E Brownell, B Mathieson, H A Young, 1987

机译：检测小鼠造血组织分离的淋巴细胞群体和细胞系中的c-rel相关转录本。
7. Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines. [O] . Brownell, E, Mathieson, B, Young, H A, 1987

机译：检测小鼠造血组织，分离的淋巴细胞群体和细胞系中的c-rel相关转录本。
8. CELL POPULATION KINETICS IN LYMPHOCYTES IN MOUSE AND RAT THYMUS [R] . Jacob I. Fabrikant, Bessie R. Foster 1972

机译：小鼠和大鼠胸腺细胞的细胞群动力学

Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines.

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