Expression of raf oncogenes activates the PEA1 transcription factor motif.

C Wasylyk; B Wasylyk; G Heidecker; M Huleihel; U R Rapp

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Expression of raf oncogenes activates the PEA1 transcription factor motif.

机译：raf癌基因的表达激活了PEA1转录因子基序。

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PEA1 (AP1) motif transcription enhancer activity was stimulated by v-raf and more efficiently by activated c-raf-1 or A-raf than by their normal counterparts, in agreement with a role for PEA1 in transformation by raf. Mutations in the ATP-binding site of v-raf prevented activation, suggesting that phosphorylation is somehow required.

机译：PEA1（AP1）基序转录增强子的活性被v-raf刺激，并且被激活的c-raf-1或A-raf比其正常对应物更有效，这与PEA1在raf转化中的作用一致。 v-raf的ATP结合位点中的突变阻止了活化，这表明以某种方式需要磷酸化。

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《Molecular and Cellular Biology》 |1989年第5期|共4页
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C Wasylyk; B Wasylyk; G Heidecker; M Huleihel; U R Rapp;
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中图分类细胞生物学;
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6. Expression of raf oncogenes activates the PEA1 transcription factor motif. [O] . C Wasylyk, B Wasylyk, G Heidecker, 1989

机译：raf癌基因的表达激活了PEA1转录因子基序。
7. Expression of raf oncogenes activates the PEA1 transcription factor motif. [O] . Wasylyk, C, Wasylyk, B, Heidecker, G, 1989

机译：raf癌基因的表达激活了PEA1转录因子基序。

Expression of raf oncogenes activates the PEA1 transcription factor motif.

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