Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation.

C J Thiele; P S Cohen; M A Israel

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Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation.

机译：维甲酸诱导分化过程中人神经母细胞瘤细胞中c-myb表达的调节。

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We detected expression of the c-myb proto-oncogene, which was initially thought to be expressed in a tissue-specific manner in cells of hematopoietic lineage, in human tissues of neuronal origin. Since the level of c-myb expression declined during fetal development, we studied the regulation of its expression in human neuroblastoma cell lines induced to differentiate by retinoic acid. The expression of c-myb declined during the maturation of neuroblastoma cells, and this change was mediated by a decrease in c-myb transcription.

机译：我们检测到c-myb原癌基因的表达，该基因最初被认为是在神经元起源的人类组织中的造血谱系细胞中以组织特异性方式表达的。由于c-myb表达水平在胎儿发育过程中下降，因此我们研究了其在视黄酸诱导分化的人神经母细胞瘤细胞系中的表达调控。 c-myb的表达在成神经细胞瘤细胞的成熟过程中下降，并且这种变化是由c-myb转录的减少介导的。

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《Molecular and Cellular Biology》 |1988年第4期|共7页
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C J Thiele; P S Cohen; M A Israel;
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中图分类细胞生物学;
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1. Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation. [J] . S E Bates, L A Mickley, Y N Chen, Molecular and Cellular Biology . 1989,第10期

机译：耐药基因在人神经母细胞瘤细胞系中的表达：视黄酸诱导的分化调控。
2. Alternative Splicing of Human Telomerase Reverse Transcriptase May Not Be Involved in Telomerase Regulation During all-trans-Retinoic Acid-Induced HL-60 Cell Differentiation. [J] . Ding J Journal of pharmacological sciences. . 2004,第2期

机译：在全反式维甲酸诱导的HL-60细胞分化过程中，可能不会参与端粒酶调控的人类端粒酶逆转录酶的选择性剪接。
3. An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation. [J] . Cerchia L, DAlessio A, Amabile G, Molecular cancer research: MCR . 2006,第7期

机译：涉及视网膜和胶质细胞源性神经营养因子的自分泌环介导视黄酸诱导的神经母细胞瘤细胞分化。
4. Retinoic Acid-Induced Human Secretin Gene Expression in Neuronal Cells Is Mediated by Cyclin-Dependent Kinase 1 [C] . LEO T.O. LEE, K.C. TAN-UN, BILLY K.C. CHOW International Symposium on VIP, PACAP, and Related Peptides . 2006

机译：视黄酸诱导的神经元细胞中的人歇基因表达由细胞周期蛋白依赖性激酶1介导
5. The effects of retinoic acid-induced differentiation on neurotransmitter receptor content and signal transduction in a human neuroblastoma cell line. [D] . Baumgartner, Melissa K. 1993

机译：视黄酸诱导的分化对人神经母细胞瘤细胞系中神经递质受体含量和信号转导的影响。
6. Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation. [O] . C J Thiele, P S Cohen, M A Israel 1988

机译：维甲酸诱导分化过程中人成神经细胞瘤细胞c-myb表达的调节。
7. Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation. [O] . Thiele, C J, Cohen, P S, Israel, M A 1988

机译：维甲酸诱导分化过程中人成神经细胞瘤细胞c-myb表达的调节。
8. Decreased Expression of N-myc Precedes Retinoic Acid-Induced Morphological Differentiation of Human Neuroblastoma [R] . Thiele, C. J., Reynolds, C. P., Israel, M. A. 1985

机译：降低N-myc表达维甲酸诱导人神经母细胞瘤形态分化

Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation.

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