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首页> 外文期刊>Molecular and Cellular Biology >Decreased expression of the stress protein HSP70 is an early event in murine erythroleukemic cell differentiation.
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Decreased expression of the stress protein HSP70 is an early event in murine erythroleukemic cell differentiation.

机译:应激蛋白HSP70的表达降低是鼠类红白血病细胞分化的早期事件。

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摘要

Two-dimensional protein gels were used to systematically assess changes in gene expression in Friend erythroleukemia cells after exposure to inducers of differentiation. A rapid decrease in expression of the stress protein HSP70 was observed after exposure to inducers. The kinetics of this change suggest that it may be related to the cellular events that regulate the onset of differentiation.
机译:二维蛋白质凝胶被用于系统地评估暴露于分化诱导剂后的朋友红白血病细胞中基因表达的变化。暴露于诱导剂后,观察到应激蛋白HSP70的表达迅速下降。这种变化的动力学表明,它可能与调节分化开始的细胞事件有关。

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