Identification of a second interferon-regulated murine Mx gene.

P Staeheli; J G Sutcliffe

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Identification of a second interferon-regulated murine Mx gene.

机译：鉴定第二个干扰素调节的鼠Mx基因。

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The murine influenza virus resistance locus Mx consists of more than one interferon-responsive transcription unit. We isolated clones of the transcripts of a second Mx gene (Mx2) which is closely linked to the well-characterized resistance gene and determined their sequences. Mx2 mRNA is more than 90% identical to Mx1 mRNA in the region corresponding to the amino termini of the encoded proteins. Mx2 mRNAs of mouse strains BALB/c and CBA have open reading frames apparently interrupted by mutations. Interferon-treated cells from strain A2G and other influenza virus-resistant strains failed to express detectable amounts of Mx2 transcripts.

机译：鼠流感病毒抗性基因座Mx由一个以上的干扰素应答转录单位组成。我们分离了第二个Mx基因（Mx2）的转录本的克隆，该基因与特征明确的抗性基因紧密相连，并确定了它们的序列。在对应于编码蛋白质的氨基末端的区域中，Mx2 mRNA与Mx1 mRNA的一致性超过90％。小鼠品系BALB / c和CBA的Mx2 mRNA具有明显被突变打断的开放阅读框。来自菌株A2G和其他耐流感病毒的菌株的干扰素处理细胞未能表达可检测量的Mx2转录本。

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《Molecular and Cellular Biology》 |1988年第10期|共5页
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P Staeheli; J G Sutcliffe;
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中图分类细胞生物学;
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1. Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons [J] . Marianne F. Fey, Graeme J. Moffat, Dennis P. Vik, Biochimica et biophysica acta. Gene structure and expression . 1996,第2a3期

机译：鼠p36（annexin II）基因的完整结构。通过交替剪接的5'非编码外显子鉴定鼠和人基因的mRNA
2. Interferon-regulated influenza virus resistance gene Mx is localized on mouse chromosome 16. [J] . P Staeheli, D Pravtcheva, L G Lundin, Journal of Virology . 1986,第3期

机译：干扰素调节的流感病毒抗性基因MX在小鼠染色体16上局部化。
3. Interferon-regulated influenza virus resistance gene Mx is localized on mouse chromosome 16. [J] . P Staeheli, D Pravtcheva, L G Lundin, Journal of Virology . 1986,第3期

机译：干扰素调节的流感病毒抗性基因MX在小鼠染色体16上局部化。
4. Identification of S-Glutathionylated Cysteine Residues in Murine Hepatic Proteins by nLC-CID-ETD MS/MS following Immunoaffinity Enrichment [C] . Susana Comte-Walters, Tiffany Ancrum, Joachim Uys, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：通过NLC-CID-ETD MS / MS在免疫亲和富集之后鉴定鼠肝蛋白中的S-谷胱甘肽化半胱氨酸残基
5. Coordination of murine limb muscle, skeleton and connective tissue development by Lmx1b. [D] . Li, Ying. 2009

机译：Lmx1b协调小鼠肢体肌肉，骨骼和结缔组织的发育。
6. Identification of a second interferon-regulated murine Mx gene. [O] . P Staeheli, J G Sutcliffe 1988

机译：鉴定第二个干扰素调节的鼠Mx基因。
7. Identification of a second interferon-regulated murine Mx gene. [O] . Staeheli, P, Sutcliffe, J G 1988

机译：鉴定第二个干扰素调节的鼠Mx基因。
8. Identification of a mutational site in exon VI of the mouse p53 gene. [R] . Paunesku, T., Gemmell, M. A., Crkvenjakov, R., 1993

机译：鉴定小鼠p53基因的外显子VI中的突变位点。

Identification of a second interferon-regulated murine Mx gene.

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