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Polycaprolactone-templated reduced-graphene oxide liquid crystal nanofibers towards biomedical applications

机译:聚己内酯为模板的氧化石墨烯还原液晶纳米纤维在生物医学中的应用

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Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO coating. We showed that coating the reduced GO (rGO) not only retains the three-dimensional topography, fiber orientation and size of the template PCL, but also makes it electroconductive. Our preliminary in vitro assessments using mesenchymal stem cells revealed no induced cytotoxicity yet increased cellular metabolism on PCL-templated rGO fibers.
机译:在这里,我们报告了一种通过在聚己内酯(PCL)垫上涂覆并随后化学还原氧化石墨烯(GO)液晶来生成导电纳米纤维的简便方法。获得的超大GO片材有利于GO涂层的电荷载流子迁移率和取向形态。我们表明,涂覆还原的GO(rGO)不仅保留了三维模板,纤维取向和模板PCL的尺寸,而且使其具有导电性。我们使用间充质干细胞进行的初步体外评估显示,在PCL模板的rGO纤维上没有诱导的细胞毒性,但增加了细胞代谢。

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