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首页> 外文期刊>RSC Advances >Mussel-inspired bio-compatible free-standing adhesive films assembled layer-by-layer with water-resistance
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Mussel-inspired bio-compatible free-standing adhesive films assembled layer-by-layer with water-resistance

机译：贻贝启发的具有生物相容性的自粘胶粘剂膜与防水层层组装

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The development of mussel-inspired materials with enhanced mechanical and physiological characteristics is fascinating due to the resulting structural properties. In this work, based on a chemical reaction, 3-(3,4-dihydroxyphenyl)propionic acid and dopamine hydrochloride (DA), with a catechol group, were covalently grafted onto a bio-compatible polymer backbone of chitosan hydrochloride (CHI) and hyaluronic acid sodium (HA). A mussel-inspired water-resistant adhesive film that could adhere in water was then fabricated by an environmentally friendly layer-by-layer (LbL) process. The water-resistant adhesive film demonstrated a strong underwater mechanical connection (0.82 ± 0.19 MPa) and a high transmittance (more than 83%) in the visible region; these characteristics are beneficial for clinical observation. A free-standing water-resistant adhesive film with a high transmittance of over 83% was also demonstrated and obtained from a facial and effective mechanical exfoliation method. The free-standing film exhibited favorable adhesion capacity with porcine skin, making it attractive for applications in the biomedical field.
机译：由于产生的结构特性，具有增强的机械和生理特性的贻贝类材料的开发令人着迷。在这项工作中，基于化学反应，将带有邻苯二酚基团的3-（3,4-二羟基苯基）丙酸和多巴胺盐酸盐（DA）共价接枝到壳聚糖盐酸盐（CHI）的生物相容性聚合物骨架上，透明质酸钠（HA）。然后，通过环保的逐层（LbL）工艺制造了可在水中粘附的贻贝类防水粘合剂膜。该耐水粘合膜在可见光区域表现出很强的水下机械连接性（0.82±0.19 MPa）和高透射率（大于83％）。这些特征对于临床观察是有益的。还证明并通过面部有效的机械剥离方法获得了具有超过83％的高透射率的自支撑的防水粘合膜。该独立式膜对猪皮肤显示出良好的粘附能力，使其在生物医学领域的应用具有吸引力。

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