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Penetrating effect of high-intensity infrared laser pulses through body tissue

机译：高强度红外激光脉冲穿透人体组织的作用

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Researchers have utilized infrared (IR) lasers as energy sources in laser therapy for curing skin diseases and skin injuries with remarkable effects. Preliminary experiments have also shown that high-intensity IR laser pulses could penetrate thick body tissues, resulting in remarkable effects for recovery from injuries in deep muscles and cartilage tissues. However, for deep-level IR laser therapy, it is unclear how much of the laser power density penetrates the body tissues at certain depths and which of the three major effects of laser irradiation, namely, laser-induced photo-chemical effect, photo-thermal effect and mechanical dragging effect, play a key role in the curing process. Thus, in this study, we developed micro-sized thin-film thermocouple (TFTC) arrays on freestanding Si _(3) N _(4) thin-film windows as sensors for laser power density and local temperature. These devices showed excellent linear responses in output voltage to laser power density with wavelengths in the range of 325–1064 nm, and also indicated the local temperature at the laser spot. We systematically measured the penetrating effect and thermal effect through thick porcine tissues for high-intensity IR pulses with a laser system used in clinical treatment and subtracted the attenuation parameters for the porcine skin, fat and muscle tissue from the experimental data. The results offered reliable quantitative references for safe irradiation doses of high-intensity IR laser pulses in practical laser therapy.
机译：研究人员已将红外线（IR）激光用作激光疗法中的能源，可有效治愈皮肤疾病和皮肤损伤。初步实验还表明，高强度的红外激光脉冲可以穿透厚的身体组织，从而为深部肌肉和软骨组织的损伤恢复提供了显着效果。但是，对于深层IR激光疗法，尚不清楚在一定深度有多少激光功率密度穿透人体组织，以及激光辐照的三大主要作用中的哪一个，即激光诱导的光化学作用，热效应和机械拖曳效应，在固化过程中起关键作用。因此，在这项研究中，我们开发了独立式Si _（3）N _（4）薄膜窗口上的微型薄膜热电偶（TFTC）阵列，作为激光功率密度和局部温度的传感器。这些设备在波长为325-1064 nm范围内的输出电压中，对激光功率密度表现出出色的线性响应，并且还指示了激光点的局部温度。我们使用临床治疗中使用的激光系统系统地测量了厚层猪组织对高强度红外脉冲的穿透效果和热效应，并从实验数据中减去了猪皮肤，脂肪和肌肉组织的衰减参数。该结果为实际激光治疗中高强度IR激光脉冲的安全辐照剂量提供了可靠的定量参考。

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