A 20 mo. old white female infant was admitted to the hospital because of a skin rash which had appeared 2 wk. before and was becoming rapidly worse. Also there was a history of eczema appearing at the age of 2 mo. This had responded to treatment with a milk substitute and had not been present for the past few months.On examination there was extensive involvement of the entire body, most marked on the extremities and genital areas, by waxy, whitish umbilicated papules from each of which a mucoid plug could be expressed. Some areas were excoriated from scratching. Physical examination was otherwise not significant. The blood count and urinalysis were normal.Smears from 1 of the lesions stained with hematoxylin and eosin showed uniform homogeneous structures indicative of molluscum contagiosum.Treatment was started with aureomycin 250 mg. every 6 hr., and moist boric acid protective dressings. One day after treatment was started the papules had begun to exfoliate and disappear. In 2 days the typical lesions had completely disappeared leaving a circular macular reddish base. On the fifth day the site of the papules had become pigmented and dry.Some nausea was noted and aureomycin ointment substituted.The infant was discharged on the seventh day with only small faint pigmented macules remaining.
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