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TREATMENT OF HEMOPHILUS INFLUENZAE b MENINGITIS

机译:甲型流感嗜血杆菌的治疗

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The present series consists of 67 patients, 17 of whom died, giving a gross fatality rate of 25.4%. Nearly one half of the cases were under 2 years of age and accounted for 65% of the deaths. By disregarding patients who died within 36 hours of admission and patients first admitted to the hospital after 21 days, the corrected fatality rate for the group below 2 years is 18.2%.Death occurred in the four patients admitted and first treated at the end of the third week of illness. Both deaths in the group under 2 years who received sulfadiazine, serum and streptomycin occurred in patients who had been ill three weeks before receiving treatment.The prognosis is likely to be unfavorable in the age group under 2 years if treatment is delayed beyond the 14th day.The fatality rate for patients who received sulfadiazine and serum was the same in this series as for patients who received streptomycin in addition.Serotherapy proved ineffectual in the age group under 2 years when delayed beyond the 14th day of illness. With respect to prognosis, the intravenous route for administration of serum offers no advantage over the intramuscular route.
机译:本系列由67例患者组成,其中17例死亡,总死亡率为25.4%。几乎一半的病例不到2岁,占死亡人数的65%。通过不考虑入院36小时内死亡的患者和21天后首次入院的患者,2岁以下组的校正病死率为18.2%.4名入院并在治疗结束时首次接受治疗的患者发生了死亡。疾病的第三周。接受磺胺嘧啶,血清和链霉素治疗的2岁以下儿童死亡均发生在接受治疗前三周的患者中。如果将治疗推迟到14天以上,则2岁以下儿童的预后可能不理想。在该系列中,接受磺胺嘧啶和血清治疗的患者的死亡率与另外接受链霉素治疗的患者的死亡率相同.2年以下年龄组的血清疗法被证明在病后第14天以后无效,因此无效。关于预后,静脉内给药血清的途径比肌内途径没有优势。

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