Based on the rationale that splanchnicectomy might interrupt a viscero-visceral autonomic reflex are responsible for bronchospasm and bronchorrhea, this operation has been performed on 24 infants and children with mucoviscidosis, most of whom were poor operative risks. Three of them died at or soon after operation, and six others have died at intervals of from 2 to 12 months postoperatively. Of the remaining 15, manifestations are essentially unchanged in five, and equivocally ameliorated in six. No information could be secured concerning the late effects in one child (Patient 17, K. W.). Three patients may have been materially benefited by the procedure.
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