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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Propagation of Measles Virus in Cultures of Chick Embryo Cells
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Propagation of Measles Virus in Cultures of Chick Embryo Cells

机译:麻疹病毒在小鸡胚胎细胞培养物中的繁殖

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This is a report from the laboratory of Dr. John F. Enders of the successful propagation of an egg-adapted strain of measles virus in cultures of chick-embryo cells throughout 24 serial passages. While the technical details will be of interest to experts in the field, the authors indicate that the quantities of measles virus which can be produced in chick cells is such that fluid from cultures of this type might provide appropriate material for the preparation of vaccine. The technique reported also has possible application to the assay of infectivity and the titration of antibodies for diagnostic and epidemiologic investigaton.
机译:这是约翰·F·恩德斯(John F. Enders)实验室的报告,该研究表明,适应卵的麻疹病毒株在24个连续传代的过程中在鸡胚细胞培养物中成功繁殖。尽管技术细节将使本领域的专家感兴趣,但作者指出,可在雏鸡细胞中产生的麻疹病毒数量如此之大,以至于这种培养物中的液体可能会为疫苗的制备提供适当的材料。所报道的技术还可能应用于传染性测定和抗体滴定,以用于诊断和流行病学调查。

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