THE RECENT cascade of knowledge of the chemistry and physiology of the protein and polypeptide hormones of the pituitary gland has been a consequence of steady progress over the past 20 years in methods of isolation, purification, and assay of these hormones. These development, while providing new insights into old problems, have raised a host of challenging and unanticipated questions. Of especial interest to students of growth is the considerable new information on growth hormone, the subject of a recent and perceptive review by Allen Root.New analytical technique utilizing immunochemical methods and radioiodinated hormone have provided specific, sensitive, and precise redioimmunoassay procedures for the measurement of the minute quanitity of human growth hormone in blood.
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