Colloid osmotic pressure of umbilical cord plasma was measured in 242 healthy infants, in 34 infants with respiratory distress syndrome (RDS), in 18 infants with asphyxia, in 13 infants who were small for gestational age, in 15 infants born to mothers with diabetes mellitus, and in 18 infants born to mothers with pregnancy-induced hypertension. In healthy infants, colloid osmotic pressure correlated highly significantly with umbilical cord blood total protein level, gestational age, and birth weight. In infants with RDS, no correlation between colloid osmotic pressure and gestational age or birth weight was found. Infants with RDS and gestational age between 36 and 38 weeks had significantly lower colloid osmotic pressure than healthy infants, whereas colloid osmotic pressure of infants with RDS and gestational age between 32 and 35 weeks did not differ from that of healthy infants of corresponding gestational age. Healthy term infants delivered by cesarean section had significantly lower colloid osmotic pressure than infants delivered vaginally. Infants with asphyxia had significantly higher colloid osmotic pressure than healthy infants. Colloid osmotic pressure is related to the lung maturity of the near-term and term neonate. Infants with a colloid osmotic pressure greater than 16 mm Hg are unlikely to develop RDS.
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机译：在242例健康婴儿，34例呼吸窘迫综合征（RDS）婴儿，18例窒息婴儿，13例小于胎龄的婴儿，15例糖尿病母亲的婴儿中测量了脐带血浆的胶体渗透压，以及母亲因妊娠高血压导致的18例婴儿。在健康的婴儿中，胶体渗透压与脐带血总蛋白水平，胎龄和出生体重高度相关。在患有RDS的婴儿中，胶体渗透压与胎龄或出生体重之间没有相关性。具有RDS和胎龄在36至38周的婴儿的胶体渗透压显着低于健康婴儿，而具有RDS和胎龄在32至35周的婴儿的胶体渗透压与相应胎龄的健康婴儿没有差异。剖宫产分娩的健康足月婴儿的胶体渗透压明显低于阴道分娩的婴儿。窒息婴儿的胶体渗透压明显高于健康婴儿。胶体渗透压与近期和足月新生儿的肺成熟度有关。胶体渗透压大于16 mm Hg的婴儿不太可能患RDS。
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