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Neurocognitive Sequelae of Scaphocephaly

机译:头颅神经认知后遗症

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Objective. Early cranioplasty for scaphocephaly has become routine in most countries. In addition to normalizing the shape of the skull, it has been found to decrease intracranial hypertension. Whether corrective surgery benefits the child's cognitive outcome has been poorly documented.Design. Eighteen children whose sagittal suture showed premature fusion at birth or soon thereafter were operated on at age 1 week to 7 months. All patients healed without complications and were followed-up at regular intervals. At the age of 7.8 to 16.3 years they were examined to clarify their neurocognitive development and to compare the results with their age- and gender-matched healthy controls.Results. Originally scaphocephalic children, although operated on, had mild deficiencies in auditory short-term memory and language development when examined with the general comprehension, similarities, and digit span subscales of the Wechsler Intelligence Scale for Children–Revised. In all other respects their developmental outcome was equal to that of the controls.Conclusions. Despite relative early correction of the skull shape, originally scaphocephalic children's neurocognitive performances do not reach the same level in all of the neurocognitive domains as their matched controls at school age. Early operation (≤1?month) may decrease this developmental delay. This implies that impairment of brain function has already taken place in utero. For the same reason an early operation seems to be justified not only for correction of the skull shape, but also to allow unrestricted development for the brain. Postponement of the operation would not serve either of these aims.
机译:目的。在大多数国家,早期颅骨成形术已经成为常规。除了使颅骨形状正常化之外,还发现它可以降低颅内高压。矫正手术是否有益于儿童的认知结果,文献报道很少。矢状缝线在出生时或之后不久出现早融合的18名儿童在1周至7个月大时接受手术。所有患者均治愈,无并发症,并定期接受随访。在7.8至16.3岁的年龄段对他们进行了检查,以阐明他们的神经认知发育并将结果与​​年龄和性别相匹配的健康对照进行比较。最初的头颅畸形儿童虽然接受了手术,但通过韦氏儿童智能量表(修订版)的一般理解,相似性和手指跨度量表进行检查后,在听觉短期记忆和语言发展方面存在轻度缺陷。在所有其他方面,它们的发育结果与对照的结果相同。尽管相对较早地校正了头骨的形状,但最初的头颅畸形儿童的神经认知能力在所有的神经认知领域都没有达到与他们的学龄期对照相同的水平。早期手术(≤1?月)可减少这种发育延迟。这意味着子宫内已经发生脑功能损害。出于同样的原因,早期手术似乎不仅对矫正颅骨形状是合理的,而且还可以使大脑不受限制地发育。推迟行动将不会实现这些目标。

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