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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Buffered Lidocaine: Analgesia for Intravenous Line Placement in Children
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Buffered Lidocaine: Analgesia for Intravenous Line Placement in Children

机译:利多卡因缓冲液:儿童静脉输注镇痛药

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Objectives . To evaluate the effectiveness of intradermal buffered lidocaine as analgesia before intravenous line (IV) placement in children.Methods . This was a randomized clinical trial undertaken in the emergency department (ED) of a regional children's hospital. Participants were children 8 to 15 years old, seen in the ED and in need of IV lines. They were enrolled by three ED nurses. Participants were randomized to receive either intradermal buffered lidocaine or no analgesia. Before placement of the IV line, patients recorded the amount of pain they were in (baseline pain) on a visual analog pain scale. The primary outcome measure was amount of pain caused by the initial IV attempt, even if that attempt was unsuccessful. This was recorded by the participant on a visual analog scale. Demographic characteristics, the number of attempts to successful placement, and the time required to place the IV line were also recorded. Differences in pain of initial IV attempt and time to place the IV line were evaluated with the Mann-Whitney U test. Differences in success of IV line placement were evaluated with the χ2 test.Results . Fifty-nine patients completed the study. Thirty received buffered lidocaine, and 29 received no analgesia before IV line placement. There was no significant difference between the two groups with regard to baseline pain or demographic characteristics. The median level of pain of the initial IV attempt as measured by the visual analog scale was 2.3 in the buffered-lidocaine group and 4.4 in the no-lidocaine group. Thirty-three percent of patients in the lidocaine group and 28% percent in the no-lidocaine group required more than one IV attempt. The median time to IV line placement was 10 minutes in the lidocaine group and 6 minutes in the no-lidocaine group.Conclusions . Use of intradermal buffered lidocaine is an effective way to diminish the pain of IV line placement in children 8 to 15 years of age. There was no difference in IV success rate in this study; however, larger numbers of patients would be required to detect statistically significant differences. We recommend the routine use of intradermal buffered lidocaine for analgesia before IV line placement in older children in all but emergent situations.
机译:目标。为了评估皮内缓冲利多卡因在小儿静脉内输注(IV)前镇痛的有效性。这是在地区儿童医院急诊室(ED)进行的一项随机临床试验。参加者为8至15岁的儿童,在急诊室看且需要静脉输液。他们由三名ED护士招募。参与者被随机分配接受皮内缓冲利多卡因或无镇痛作用。在放置IV线之前,患者以视觉模拟疼痛量表记录他们所遭受的疼痛量(基线疼痛)。主要的结局指标是最初的静脉内尝试导致的疼痛程度,即使尝试未成功也是如此。参与者以视觉模拟量表记录了这一情况。还记录了人口统计特征,成功放置尝试的次数以及放置IV线所需的时间。用Mann-Whitney U检验评估了初次IV尝试的疼痛和放置IV线的时间的差异。用χ2检验评估IV线放置成功的差异。 59名患者完成了研究。 30例接受利多卡因缓冲液治疗,29例未行静脉输液前镇痛。两组在基线疼痛或人口统计学特征方面无显着差异。通过视觉模拟量表测量的初始IV尝试疼痛的中位水平在缓冲的利多卡因组中为2.3,在非利多卡因组中为4.4。利多卡因组中33%的患者和非利多卡因组中28%的患者需要进行IV次以上尝试。利多卡因组至IV线放置的中位时间为10分钟,非利多卡因组为6分钟。皮内缓冲利多卡因的使用是减轻8至15岁儿童输液管线疼痛的有效方法。这项研究的IV成功率没有差异。但是,将需要大量患者来检测统计学上的显着差异。我们建议在除紧急情况外的其他所有年龄较大的儿童中常规使用皮内缓冲利多卡因镇痛,然后再进行静脉输液。

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