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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >An Orange a Day Keeps the Doctor Away: Scurvy in the Year 2000
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An Orange a Day Keeps the Doctor Away: Scurvy in the Year 2000

机译:每天吃橙子远离医生:2000年的坏血病

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Scurvy has been known since ancient times, but the discovery of the link between the dietary deficiency of ascorbic acid and scurvy has dramatically reduced its incidence over the past half-century. Sporadic reports of scurvy still occur, primarily in elderly, isolated individuals with alcoholism. The incidence of scurvy in the pediatric population is very uncommon, and it is usually seen in children with severely restricted diets attributable to psychiatric or developmental problems. The condition is characterized by perifollicular petechiae and bruising, gingival inflammation and bleeding, and, in children, bone disease. We describe a case of scurvy in a 9-year-old developmentally delayed girl who had a diet markedly deficient in vitamin C resulting from extremely limited food preferences. She presented with debilitating bone pain, inflammatory gingival disease, perifollicular hyperkeratosis, and purpura. Severe hypertension without another apparent secondary cause was also present, which has been previously undescribed. The signs of scurvy and hypertension resolved after treatment with vitamin C. The diagnosis of scurvy is made on clinical and radiographic grounds, and may be supported by finding reduced levels of vitamin C in serum or buffy-coat leukocytes. The response to vitamin C is dramatic. Clinicians should be aware of this potentially fatal but easily curable condition that is still occasionally encountered among children.
机译:坏血病自古以来就广为人知,但在过去的半个世纪中,饮食中抗坏血酸与坏血病之间的联系的发现大大降低了其发病率。坏血病的报告仍然零星出现,主要发生在酗酒的老年人中。患儿坏血病的发生率非常少见,通常在因精神病或发育问题而饮食受到严格限制的儿童中常见。该病的特征是毛囊周围有瘀点和瘀伤,牙龈发炎和出血,儿童则有骨病。我们描述了一个9岁,发育迟缓的女孩患坏血病的案例,该女孩的饮食因极有限的饮食偏爱而导致维生素C明显缺乏。她表现出令人衰弱的骨痛,炎性牙龈疾病,滤泡性角化过度和紫癜。还存在严重的高血压,没有其他明显的继发性原因,这以前没有描述过。用维生素C治疗后,坏血病和高血压的症状消失了。坏血病的诊断是基于临床和影像学检查,可以通过发现血清或血沉棕黄层白细胞中维生素C含量降低来支持。对维生素C的反应是惊人的。临床医生应该意识到这种潜在的致命性但容易治愈的疾病,仍然在儿童中偶尔遇到。

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