OBJECTIVES. We aimed to determine the correlation between end-tidal carbon dioxide levels and serum bicarbonate concentrations among patients with gastroenteritis, to compare the end-tidal carbon dioxide with other clinical parameters that might also be associated with the degree of acidosis, and to examine the relationship between end-tidal carbon dioxide levels and return visits.METHODS. Our prospective sample included patients presenting to the emergency department with a chief complaint of vomiting and/or diarrhea. The association between end-tidal carbon dioxides and serum bicarbonate concentrations was determined with simple linear-regression analysis. Receiver operating characteristic curves were computed to determine the predictive ability of the end-tidal carbon dioxide to detect metabolic acidosis.RESULTS. One hundred thirty of 146 subjects who were approached were included in the final analysis. For those for whom laboratory studies were performed, the mean serum bicarbonate concentration was 17.3 ± 4.3 mmol/L and the mean end-tidal carbon dioxide level was 34.2 ± 5.2 mm Hg. End-tidal carbon dioxide levels and serum bicarbonate concentrations were correlated linearly in bivariate analysis. Receiver operating characteristic curves were calculated for end-tidal carbon dioxide as a predictor of serum bicarbonate concentrations of ≤13, ≤15, and ≤17 mmol/L, with areas under the curves of 0.94, 0.95, and 0.90, respectively. The relationship between end-tidal carbon dioxide levels and serum bicarbonate concentrations was independent of other potential predictors of acidosis in multivariable analysis. The mean end-tidal carbon dioxide level for patients who required an unanticipated return visit (33.0 ± 4.0 mm Hg) was lower than the level for those who did not seek reevaluation (36.6 ± 3.6 mm Hg).CONCLUSIONS. End-tidal carbon dioxide levels were correlated with serum bicarbonate concentrations among children with vomiting and diarrhea, independent of other clinical parameters. Capnography offers an objective noninvasive measure of the severity of acidosis among patients with gastroenteritis.
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机译：目标我们旨在确定肠胃炎患者中潮气末二氧化碳水平与血清碳酸氢盐浓度之间的相关性，以比较潮气末二氧化碳与可能也与酸中毒程度相关的其他临床参数，并探讨其关系。在潮气末二氧化碳水平和回访之间。我们的前瞻性样本包括主要就呕吐和/或腹泻向急诊科就诊的患者。潮气中二氧化碳与血清碳酸氢盐浓度之间的关联通过简单的线性回归分析确定。计算接收者的工作特征曲线，以确定潮气末二氧化碳检测代谢性酸中毒的预测能力。最终分析中包括了146名被访者中的130名。对于进行了实验室研究的患者，血清碳酸氢盐的平均浓度为17.3±4.3 mmol / L，潮气末二氧化碳的平均水平为34.2±5.2 mm Hg。在二变量分析中，潮气末二氧化碳水平和血清碳酸氢盐浓度线性相关。计算出潮气中二氧化碳的接收器工作特性曲线，作为血清碳酸氢盐浓度≤13，≤15和≤17mmol / L的预测指标，曲线下的面积分别为0.94、0.95和0.90。在多变量分析中，潮气末二氧化碳水平与血清碳酸氢盐浓度之间的关系与酸中毒的其他潜在预测因子无关。需要意外回诊的患者的平均潮气末二氧化碳水平（33.0±4.0 mm Hg）低于不进行重新评估的患者的平均呼气末二氧化碳水平（36.6±3.6 mm Hg）。结论。呕吐和腹泻儿童的潮气末二氧化碳水平与血清碳酸氢盐浓度相关，与其他临床参数无关。二氧化碳图提供了一种客观的非侵入性措施，可评估胃肠炎患者酸中毒的严重程度。
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