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Formation of a double salt of phosphatidylcholine and zinc chloride

机译:磷脂酰胆碱和氯化锌复盐的形成

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pZnCl2 forms a 1 : 1 double salt with phosphatidylcholine. This compound resembles the long-known double salt of CdCl2 and phosphatidylcholine except that the latter has the composition (CdCl2)3(phosphatidylcholine)2. Treatment of phosphatidylcholine with a mixture of equimolar amounts of ZnCl2 and CdCl2 yields the ZnCl2 double salt. The ZnCl2 double salt can be obtained as an amorphous flocculent precipitate and as small spherules. These results are discussed in relation to the toxic action of cadmium salts on the mammalian testis and to the protection afforded by zinc salts. It is suggested that membrane phospholipids are essential components of specific sites for reversible binding of Zn2+ and Cd2+./p
机译:ZnCl 2与磷脂酰胆碱形成1:1复盐。该化合物类似于众所周知的CdCl2和磷脂酰胆碱的复盐,除了后者具有(CdCl2)3(磷脂酰胆碱)2的组成。用等摩尔量的ZnCl2和CdCl2的混合物处理磷脂酰胆碱,得到ZnCl2复盐。 ZnCl2复盐可作为无定形絮凝沉淀物和小球获得。讨论了有关镉盐对哺乳动物睾丸的毒性作用以及锌盐提供的保护作用的这些结果。提示膜磷脂是Zn2 +和Cd2 +可逆结合的特定位点的重要组成部分。

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