Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC).

M Adachi; M Hayami; N Kashiwagi; T Mizuta; Y Ohta; M J Gill; D S Matheson; T Tamaoki; C Shiozawa; S Hakomori

首页> 外文期刊>The Journal of Experomental Medicine >Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC).

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Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC).

机译：Ley抗原在人免疫缺陷病毒感染的人T细胞系中以及获得性免疫缺陷综合症（AIDS）和AIDS相关复合物（ARC）患者的外周淋巴细胞中的表达。

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Ley determinant (Fuc alpha 1---|-2Gal beta 1---|-4[Fuc alpha 1---|-3]GlcNAc beta 1---|-R) defined by mAb BM-1 is highly expressed in human immunodeficiency virus (HIV)-infected T cell lines and in CD3+ peripheral mature T cells of patients with acquired immune deficiency syndrome (AIDS) or with AIDS-related complex (ARC). Ley expression increased greatly in the CD3+ population in the advanced stage of AIDS when the CD4+ population decreased greatly. Six other carbohydrate antigens tested by their respective mAbs were not detected in these same cells. None of the carbohydrate antigens tested by the seven mAbs used in this study were found in noninfected T cell lines and in normal peripheral blood lymphocytes.

机译：由mAb BM-定义的Ley行列式（Fuc alpha 1 --- | -2Gal beta 1 --- | -4 [Fuc alpha 1 --- | -3] GlcNAc beta 1 --- | -R） 1在人免疫缺陷病毒（HIV）感染的T细胞系和获得性免疫缺陷综合症（AIDS）或艾滋病相关综合症（ARC）的患者的CD3 +外周成熟T细胞中高表达。当CD4 +种群大大减少时，艾滋病晚期的CD3 +种群中Ley表达大大增加。在这些相同的细胞中未检测到通过其各自的单克隆抗体测试的其他六种碳水化合物抗原。在未感染的T细胞系和正常外周血淋巴细胞中均未发现通过本研究中使用的7种单克隆抗体测试的碳水化合物抗原。

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《The Journal of Experomental Medicine》 |1988年第2期|共9页
作者
M Adachi; M Hayami; N Kashiwagi; T Mizuta; Y Ohta; M J Gill; D S Matheson; T Tamaoki; C Shiozawa; S Hakomori;
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中图分类医用一般科学;
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6. Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) [O] . 1988

机译：Ley抗原在人免疫缺陷病毒感染的人T细胞系中以及获得性免疫缺陷综合症（AIDS）和AIDS相关复合物（ARC）患者的外周淋巴细胞中的表达
7. Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) [O] . 1988

机译：Ley抗原在人免疫缺陷病毒感染的人T细胞系中以及获得性免疫缺陷综合症（AIDS）和AIDS相关复合物（ARC）患者的外周淋巴细胞中的表达

Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC).

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