Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos

Hidefumi Yoshioka; Yoshiyasu Ishimaru; Noriyuki Sugiyama; Naoki Tsunekawa; Toshiaki Noce; Megumi Kasahara; Ken-ichirou Morohashi

首页> 外文期刊>Developmental biology >Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos

【24h】

Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos

机译：中肾FGF信号传导与鸡胚性冷淡性腺原基的发展有关

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Thegonadaswellasthereproductivetracts,kidney,andadrenalcortexarederivedfromtheintermediatemesoderm.Inaddition,theintermediatemesodermformsthemesonephros.Althoughthemesonephrosisthesourceofcertaintesticularcelltypes,itscontributiontogonadformationthroughexpressionofgrowthfactorsislargelyunknown.Here,weexaminedtheexpressionprofilesofemFGF9/eminthedevelopingmesonephrosofchickembryosatsexuallyindifferentstages,andfoundthattheexpressiondomainisadjacenttothegonadalprimordium.Moreover,emFGFR3/em(emFGFreceptor3/em)showedastrongexpressioninthegonadalprimordium.Next,weexaminedthefunctionsofFGFsignalduringgonadaldevelopmentwithmisexpressedemFGF9/em.Interestingly,misexpressionofemFGF9/emledtogonadalexpansionthroughstimulationofcellproliferation.Incontrast,treatmentwithachemicalinhibitorforFGFRdecreasedcellproliferationandresultedinreductionofthegonadalsize.Simultaneously,thetreatmentresultedinreductionofgonadalmarkergeneexpression.OurstudydemonstratedthatemFGF/emexpressedinthedevelopingmesonephrosisinvolvedinthedevelopmentofthegonadatthesexuallyindifferentstagesthroughstimulationofgonadalcellproliferationandgonadalmarkergeneexpression./p/div

机译：Thegonadaswellasthereproductivetracts，肾，andadrenalcortexarederivedfromtheintermediatemesoderm.Inaddition，theintermediatemesodermformsthemesonephros.Althoughthemesonephrosisthesourceofcertaintesticularcelltypes，itscontributiontogonadformationthroughexpressionofgrowthfactorsislargelyunknown.Here，weexaminedtheexpressionprofilesof <位置> FGF9 的inthedevelopingmesonephrosofchickembryosatsexuallyindifferentstages，andfoundthattheexpressiondomainisadjacenttothegonadalprimordium.Moreover，<位置> FGFR3 的（<在> FGFreceptor3 的）showedastrongexpressioninthegonadalprimordium的.next，weexaminedthefunctionsofFGFsignalduringgonadaldevelopmentwithmisexpressed FGF9 有意思的，misexpressionof FGF9 ledtogonadalexpansionthroughstimulationofcellproliferation.Incontrast，treatmentwithachemicalinhibitorforFGFRdecreasedcellproliferationandresultedinreductionofthegonadalsize.Simultaneously，thetreatmentresultedinreductionofgonadalmarkergeneexpression.Ourstudydemonstratedthat FGF expressedin通过刺激性腺细胞增殖和性腺标志物基因表达，不同程度的性腺发育涉及性腺病的发展。 展开▼

著录项

来源
《Developmental biology》 |2005年第1期|共页

作者
Hidefumi Yoshioka; Yoshiyasu Ishimaru; Noriyuki Sugiyama; Naoki Tsunekawa; Toshiaki Noce; Megumi Kasahara; Ken-ichirou Morohashi;
展开▼

作者单位

展开▼

收录信息

原文格式 PDF

正文语种

中图分类生物科学;

关键词

相似文献

外文文献

中文文献

专利

1. Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos [J] . Yoshioka H, Ishimaru Y, Sugiyama N, Developmental biology . 2005,第1期

机译：中肾FGF信号传导与鸡胚性冷淡性腺原基的发展有关

2. Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate [J] . Anastasiya S. Ivanova, Andrey G. Zaraisky, Galina V. Ermakova, Biology Open . 2014,第3期

机译：Ras-dva1小GTPase通过控制神经板前缘的Fgf8和Agr信号调节非洲爪蟾胚胎端脑发育Ras-dva1小GTPase通过控制神经板前缘的Fgf8和Agr信号调节非洲爪蟾胚胎端脑发育。神经板Ras-dva1小GTPase通过控制神经板前缘的Fgf8和Agr信号调节非洲爪蟾胚胎的端脑发育

3. Role of FGF signalling in neural crest cell migration during early chick embryo development [J] . Zhang Xiao-tan, Wang Guang, Li Yan, Zygote . 2018,第6期

机译：FGF信号传导在鸡胚胚胎发育期间神经嵴细胞迁移的作用

4. Ciprofloxacin effect on the Fgf10 gene expression in chicken embryo (Gallus gallus domesticus) limb development [C] . Dwi Listyorini, Nursasi Handayani, Qoniatul Munawaroh, International Conference on Biological Science . 2018

机译：环丙沙星对鸡胚中FGF10基因表达的影响（Gallus Gallus Domesticus）肢体发育

5. Tissue interactions and molecular factors involved in indifferent gonad specification in the avian embryo [D] . Scott, Jamil Bennette 2008

机译：禽胚胎中性腺规格无关的组织相互作用和分子因素

6. A right-sided pathway involving FGF8/Snai1 controls asymmetric development of the proepicardium in the chick embryo [O] . Jan Schlueter, Thomas Brand 2009

机译：涉及FGF8 / Snai1的右侧途径控制雏鸡胚胎中前皮的不对称发育

7. Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos [O] . Yoshioka Hidefumi, Ishimaru Yoshiyasu, Sugiyama Noriyuki, 2005

机译：中肾FGF信号传导与鸡胚性冷淡性腺原基的发育有关

8. Effects of Continuous Radiation on Chick Embryos and Developing Chicks. 1. Growth Rate, Gonads, and Bone. [R] . Warren, S., Dixon, F. J. 1949

机译：在鸡胚连续辐射和发展小鸡的影响。 1.增长率，性腺和骨。

1. FGF受体-1和FGF受体-2介导成纤维细胞生长因子-21信号传导 [J] . 任桂萍 ,尹杰超 ,王文飞 . 中国科学 . 2010,第004期

2. FGF8、 SHH、FOXL2基因在鸡胚成纤维细胞中的调控作用研究 [J] . 张虎军 ,赵宗胜 ,翟曼君 . 石河子大学学报（自然科学版） . 2017,第005期

3. FGF10对鸡胚尿囊膜血管形成的影响 [J] . 刘芳 ,李刚 ,张丝雨 . 安徽医科大学学报 . 2017,第002期

4. FGF23/α-Klotho信号传导的分子机制 [J] . 陈高帜 ,李校堃 . 生物产业技术 . 2018,第005期

5. 主动脉-性腺-中肾区、卵黄囊和循环血来源的CD41+细胞分化潜能比较 [J] . 李思霆 ,周军年 ,陈海旭 . 中华血液学杂志 . 2013,第010期

6. 成纤维生长因子8(FGF8)对鸡胚胎干细胞向精原干细胞分化的研究 [C] . 王曼 ,金晶 ,张文慧 . 江苏省畜牧兽医学会2017年学术年会 . 2017

7. FGF家族生物信息学分析及FGF9/16/20亚家族在罗非鱼性腺发育中的可能作用 [A] . 曾圣 . 2012

1. 一种高效的通过胚胎移植技术构建嵌合体性腺鸡胚的方法 [P] . 中国专利： CN111793652A . 2020-10-20

2. Ways to stimulate immunity and Development immunocompetent organs chick embryos during incubation [P] . 外国专利： RU2008121653A . 2009-12-10

机译：孵育过程中刺激免疫和发育具有免疫功能的器官雏鸡胚胎的方法

相关主题

Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos

摘要

著录项

相似文献

相关主题

期刊订阅