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首页> 外文期刊>Journal of Clinical Microbiology >The urinary bladder, a consistent source of Borrelia burgdorferi in experimentally infected white-footed mice (Peromyscus leucopus).
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The urinary bladder, a consistent source of Borrelia burgdorferi in experimentally infected white-footed mice (Peromyscus leucopus).

机译：膀胱是实验感染的白脚小鼠（Peromyscus leucopus）的伯氏疏螺旋体的一致来源。

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摘要

White-footed mice, Peromyscus leucopus, were experimentally infected in the laboratory with Borrelia burgdorferi, the causative agent of Lyme disease. After mice were infected by intraperitoneal or subcutaneous inoculation or by tick bite, attempts were made to culture spirochetes from the urinary bladder, spleen, kidney, blood, and urine. Spirochetes were most frequently isolated from the bladder (94%), followed by the kidney (75%), spleen (61%), and blood (13%). No spirochetes were isolated from the urine. Tissue sectioning and immunofluorescence staining of the urinary bladder demonstrated spirochetes within the bladder wall. The results demonstrate that cultivation of the urinary bladder is very effective at isolating B. burgdorferi from experimentally infected white-footed mice and that culturing this organ may be productive when surveying wild rodents for infection with this spirochete.
机译：在实验室中，白脚小鼠白粉病菌被实验感染了莱姆病的病原体伯氏疏螺旋体。在通过腹膜内或皮下接种或tick咬感染小鼠后，尝试从膀胱，脾脏，肾脏，血液和尿液培养螺旋体。经常从膀胱（94％）中分离螺旋体，其次是肾脏（75％），脾脏（61％）和血液（13％）。没有从尿液中分离出螺旋体。膀胱的组织切片和免疫荧光染色显示膀胱壁内有螺旋体。结果表明，膀胱的培养非常有效地从实验感染的白脚小鼠中分离出伯氏疏螺旋体，并且当调查野生啮齿类动物对这种螺旋体的感染时，培养该器官可能具有生产性。

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