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首页> 外文期刊>Journal of Clinical Microbiology >Sampling efficiency in the diagnosis of Helicobacter pylori infection and chronic active gastritis.
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Sampling efficiency in the diagnosis of Helicobacter pylori infection and chronic active gastritis.

机译：诊断幽门螺杆菌感染和慢性活动性胃炎的采样效率。

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摘要

The methods and sampling procedures used in the diagnosis of Helicobacter pylori infection and chronic active gastritis were evaluated. Five biopsy specimens for bacteriological cultivation and three specimens for histological examination were obtained endoscopically from a defined area of the gastric antral mucosae of 83 patients. An increase in the number of biopsy specimens for cultivation from one to five revealed only one more H. pylori-infected patient. H. pylori was isolated from 31 of 83 patients. Three technically adequate samples for histological examination were obtained from each of 74 patients. Of these 74 patients, chronic active gastritis was diagnosed by demonstration of typical histological changes in all three specimens from each of 20 patients, in two of three specimens from each of 3 patients, and in one of three specimens from 1 patient. The results indicate that one biopsy specimen is sufficient for the isolation of H. pylori, whereas several specimens may be necessary for the histological diagnosis. Chronic active gastritis was found in four patients not infected with H. pylori; on the other hand, H. pylori was isolated from nine patients who showed no signs of chronic active gastritis in any of three samples.
机译：评估了用于诊断幽门螺杆菌感染和慢性活动性胃炎的方法和采样程序。从83名患者的胃窦粘膜的限定区域内窥镜下获得了五个用于细菌培养的活检标本和三个用于组织学检查的标本。用于培养的活检标本数量从一处增加到五处，表明仅另外一名幽门螺杆菌感染患者。幽门螺杆菌分离自83例患者中的31例。从74例患者中每人获得了三个用于组织学检查的技术上足够的样本。在这74例患者中，慢性活动性胃炎是通过证实20例患者的所有三个样本，3例患者的三个样本中的两个以及1例患者的三个样本中的一个典型的组织学变化来诊断的。结果表明，一个活检标本足以分离幽门螺杆菌，而几个标本可能需要进行组织学诊断。在四名未感染幽门螺杆菌的患者中发现了慢性活动性胃炎。另一方面，幽门螺杆菌是从九名患者中分离出来的，这些患者在三个样本中均未显示出慢性活动性胃炎的迹象。

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