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首页> 外文期刊>Journal of Clinical Microbiology >Evaluation of the card test for diagnosis of human brucellosis.
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Evaluation of the card test for diagnosis of human brucellosis.

机译：评估卡测试对人类布鲁氏菌病的诊断。

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The relative efficacy of the card test in the diagnosis of human brucellosis was evaluated by comparison with four other tests: the standard tube agglutination test, centrifugation agglutination test, 2-mercaptoethanol degradation technique, and 2-mercaptoethanol centrifugation agglutination test. A total of 1,701 serum specimens from persons with various degrees of potential exposure to brucella organisms or cross-reactive antigens were used in this study. In comparison with standard tube agglutination results, the card test had a sensitivity of 95.3% and a specificity of 84.1%. The card-test antigen was nonreactive with serum specimens from tularemia patients and cholera vaccinees. Our data indicated that this test measures both immunoglobulin G and immunoglobulin M agglutinins. The value of the card test in the presumptive serological diagnosis of clinical brucellosis in humans appears to be low; however, the card test may be of value in serological surveys to delineate high-risk populations.
机译：通过与其他四项测试进行比较，评估卡测试在诊断人类布鲁氏菌病中的相对功效：标准试管凝集试验，离心凝集试验，2-巯基乙醇降解技术和2-巯基乙醇离心凝集试验。这项研究共使用了来自不同程度的布鲁氏菌生物或交叉反应性抗原暴露人群的1,701份血清标本。与标准试管凝集结果相比，卡片测试的灵敏度为95.3％，特异性为84.1％。卡测试抗原与Tularemia患者和霍乱疫苗的血清标本无反应。我们的数据表明，该测试可同时测量免疫球蛋白G和免疫球蛋白M凝集素。卡测试在人类临床布鲁氏菌病的血清学诊断中的价值似乎很低。但是，卡片测试可能在血清学调查中有价值，以描绘出高危人群。

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