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首页> 外文期刊>Journal of Clinical Microbiology >Detection of Campylobacter pyloridis in patients with antrum gastritis and peptic ulcers by culture, complement fixation test, and immunoblot.
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Detection of Campylobacter pyloridis in patients with antrum gastritis and peptic ulcers by culture, complement fixation test, and immunoblot.

机译：通过培养，补体固定试验和免疫印迹法检测胃窦炎和消化性溃疡患者中的幽门弯曲菌。

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摘要

The association of Campylobacter pyloridis with antrum gastritis and peptic ulcers was described. We investigated antral biopsies from 180 patients who underwent gastroscopy. By culture or Gram stain or both, we found overall 98 (54%) of them to be positive for C. pyloridis. In the various groups the following percentages were found to be positive: normal antral mucosa 3% (n = 30); moderate superficial antrum gastritis, 49% (n = 83); severe superficial antrum gastritis, 86% (n = 44); duodenal ulcer, 83% (n = 54); and gastric ulcer, 72% (n = 18). A serological screening that used a complement fixation test yielded the following results: highest rates of positive complement fixation titers were seen in patients with severe gastritis and those with duodenal ulcers, both with 79%; the lowest incidence was in a group of 20 blood donors, with 5%. Positive complement fixation titers in gastritis patients also correlated well with characteristic patterns on immunoglobulin G and A immunoblots, while there was no specific reactivity observed on immunoglobulin M immunoblots.
机译：描述了幽门弯曲杆菌与胃窦炎和消化性溃疡的关系。我们调查了180例行胃镜检查的患者的肛门活检。通过培养或革兰氏染色或两者，我们发现其中总共98个（54％）对幽门螺旋杆菌呈阳性。在各个组中，发现以下百分比为阳性：正常肛门黏膜3％（n = 30）;中度浅表胃炎，49％（n = 83）;严重的浅表胃炎，86％（n = 44）;十二指肠溃疡，83％（n = 54）;和胃溃疡，占72％（n = 18）。使用补体结合试验的血清学筛查得到以下结果：严重胃炎和十二指肠溃疡患者中补体结合滴度阳性率最高，均为79％;重度胃炎和十二指肠溃疡患者中，补体结合效价最高。发生率最低的是20名献血者，占5％。胃炎患者补体固定滴度的阳性也与免疫球蛋白G和A免疫印迹的特征模式密切相关，而在免疫球蛋白M免疫印迹上未观察到特异性反应。

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