Development and Evaluation of an Epstein-Barr Virus (EBV) Immunoglobulin M Enzyme-Linked Immunosorbent Assay Based on the 18-Kilodalton Matrix Protein for Diagnosis of Primary EBV Infection

K. H. Chan; R. X. Luo; H. L. Chen; M. H. Ng; W. H. Seto; J. S. M. Peiris

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Development and Evaluation of an Epstein-Barr Virus (EBV) Immunoglobulin M Enzyme-Linked Immunosorbent Assay Based on the 18-Kilodalton Matrix Protein for Diagnosis of Primary EBV Infection

机译：基于18 Kilodalton基质蛋白的爱泼斯坦-巴尔病毒（EBV）免疫球蛋白M酶联免疫吸附试验的开发和评估，用于诊断原发性EBV感染

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A new immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA) based on the recombinant Epstein-Barr virus (EBV) matrix protein was developed. Compared to indirect immunofluorescence for the detection of IgM antibody to the EBV capsid antigen on clinical specimens, the sensitivity and specificity of the new IgM ELISA were 96 and 96%, respectively.

机译：基于重组爱泼斯坦-巴尔病毒（EBV）基质蛋白的新的免疫球蛋白M（IgM）酶联免疫吸附测定（ELISA）。与间接免疫荧光检测临床标本中针对EBV衣壳抗原的IgM抗体相比，新IgM ELISA的敏感性和特异性分别为96％和96％。

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《Journal of Clinical Microbiology》 |1998年第11期|共3页
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K. H. Chan; R. X. Luo; H. L. Chen; M. H. Ng; W. H. Seto; J. S. M. Peiris;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Evaluation of an Epstein-Barr Virus (EBV) Immunoglobulin M Enzyme-Linked Immunosorbent Assay Using a Synthetic Convergent Peptide Library, or Mixotope, for Diagnosis of Primary EBV Infection [J] . D. Tranchand-Bunel, H. Gras-Masse, B. Bourez, Journal of Clinical Microbiology . 1999,第7期

机译：EB免疫球蛋白M酶联免疫吸附测定的评估，使用合成的聚合肽文库或Mixotope诊断原发性EBV感染
2. Evaluation of three commercial enzyme-linked immunosorbent assays and two latex agglutination assays for diagnosis of primary Epstein-Barr virus infection. [J] . A Svahn, M Magnusson, L J?gdahl, Journal of Clinical Microbiology . 1997,第11期

机译：评价三种诊断原发性爱泼斯坦-巴尔病毒感染的酶联免疫吸附测定法和两种乳胶凝集测定法。
3. Performance of an immunofiltration assay detecting IgM antibodies against ZEBRA and viral capsid p18 proteins (Immunoquick ? filtration EBV M) for the diagnosis of heterophile antibody-negative primary Epstein-Barr virus infection in children [J] . MezaL.D., Sancho-TelloS., Mu?oz-CoboB., Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology . 2012,第3期

机译：免疫过滤试验检测针对ZEBRA和病毒衣壳p18蛋白的IgM抗体（Immunoquick®过滤EBV M）在诊断儿童嗜异性抗体阴性原发性爱泼斯坦-巴尔病毒中的作用
4. Design and Evaluation of Protein Expression in a Recombinant Plasmid Encoding Epitope gp 350/220 of the Epstein-Barr Virus (EBV) [C] . Karimatul Himmah, Nurul Dluha, Nadya V. M. Anyndita, International Conference on Global Resource Conservation . 2017

机译：Epstein-Barr病毒（EBV）重组质粒蛋白表达蛋白质表达的设计与评价（EBV），ZHP750 / 220
5. Development of a monoclonal antibody-based antigen detection enzyme-linked immunosorbent assay (ELISA) for the diagnosis of human toxoplasmosis. [D] . Grushka, Daniel. 2001

机译：基于单克隆抗体的抗原检测酶联免疫吸附测定（ELISA）的开发，用于诊断人类弓形虫病。
6. Note: Development and Evaluation of an Epstein-Barr Virus (EBV) Immunoglobulin M Enzyme-Linked Immunosorbent Assay Based on the 18-Kilodalton Matrix Protein for Diagnosis of Primary EBV Infection [O] . K. H. Chan, R. X. Luo, H. L. Chen, 1998

机译：注意：基于18-Kiddalton基质蛋白的爱泼斯坦-巴尔病毒（EBV）免疫球蛋白M酶联免疫吸附试验的开发和评估用于诊断原发性EBV感染
7. Application of Virus-Specific Immunoglobulin M (IgM), IgG, and IgA Antibody Detection with a Polyantigenic Enzyme-Linked Immunosorbent Assay for Diagnosis of Epstein-Barr Virus Infections in Childhood [O] . Schaade, Lars, Kleines, Michael, Häusler, Martin Georg 2001

机译：病毒特异性免疫球蛋白M（IgM），IgG和IgA抗体检测与多抗原酶联免疫吸附法在儿童爱泼斯坦-巴尔病毒感染诊断中的应用
8. Purification of a Baculovirus-Expressed Hepatitis E Virus Structural Protein andUtility in an Enzyme-Linked Immunosorbent Assay [R] . He, J., Ching, W. M., Yarbough, P., 1995

机译：杆状病毒表达的戊型肝炎病毒结构蛋白的纯化和酶联免疫吸附试验的实用性

Development and Evaluation of an Epstein-Barr Virus (EBV) Immunoglobulin M Enzyme-Linked Immunosorbent Assay Based on the 18-Kilodalton Matrix Protein for Diagnosis of Primary EBV Infection

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