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首页> 外文期刊>Journal of Clinical Microbiology >Reservoir of four organisms associated with bacterial vaginosis suggests lack of sexual transmission.
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Reservoir of four organisms associated with bacterial vaginosis suggests lack of sexual transmission.

机译:与细菌性阴道病相关的四种生物的储库表明缺乏性传播。

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This study consisted of a search for the possible reservoir and mode of spread of the four bacterial vaginosis-associated organisms Mobiluncus mulieris, Mobiluncus curtisii, Mycoplasma hominis, and Gardnerella vaginalis. Their occurrence in rectal, oral, and pharyngeal specimens from women with and without bacterial vaginosis, their male sexual consorts, four homosexual men, and children (altogether, 374 people) was studied. Genital samples were also obtained from all adults. All four organisms were isolated from the rectums of 45 to 62% of women with bacterial vaginosis and 10 to 14% of women without bacterial vaginosis. They also occurred in the rectums of males and children. M. hominis was recovered from the oropharynxes of 12 adults whose sexual consorts had genital occurrences of the organism. Mobiluncus spp. occurred only in the vaginas of women with bacterial vaginosis (97%). The organisms were only infrequently recovered from genital samples from 135 males. Organisms were recovered from the urethras and/or coronal sulci of 10 of 44 male consorts of women with bacterial vaginosis. However, after 2 weeks of condom use during sexual intercourse, only M. hominis remained in the urethra of one man. These findings suggest that the organisms associated with bacterial vaginosis are not spread sexually but colonize the vagina from an endogenous intestinal tract site. The pathophysiological mechanisms leading to bacterial vaginosis in a subpopulation of all women are still unknown.
机译:这项研究包括寻找四种与细菌性阴道病相关的微生物,即Mobiluncus mulieris,Mobiluncus curtisii,人支原体和阴道加德纳菌的可能的贮藏库和传播方式。研究人员在有,无细菌性阴道病的女性,男性性伴侣,四名同性恋者和儿童(共374人)的直肠,口腔和咽部样本中发现它们的发生。还从所有成年人身上获得生殖器样本。从细菌性阴道病的女性直肠中分离出所有四种微生物,其中女性细菌性阴道病的女性占45%至62%,而细菌性阴道病的女性直肠中则分离出10%至14%。它们也发生在男性和儿童的直肠中。从12名成年人的口咽中发现了人型支原体,他们的性伴侣有该器官的生殖器。 Mobiluncus spp。仅发生在细菌性阴道病女性的阴道中(97%)。仅从135例雄性的生殖器样本中很少发现这种生物。从44名患有细菌性阴道病的男性配偶中的10个从尿道和/或冠状沟中回收生物。但是,在性交期间使用安全套2周后,只有人型支原体仍留在一个男人的尿道中。这些发现表明,与细菌性阴道病有关的生物没有通过性传播,而是从内源性肠道部位定居在阴道中。导致所有妇女亚群中细菌性阴道病的病理生理机制仍然未知。

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