...
首页> 外文期刊>Journal of Clinical Microbiology >Comparison of kinetic and end-point diffusion methods for quantitating human serum immunoglobulins.
【24h】

Comparison of kinetic and end-point diffusion methods for quantitating human serum immunoglobulins.

机译:动力学和终点扩散法定量人血清免疫球蛋白的比较。

获取原文
           

摘要

Proficiency testing results were used to compare the kinetic and end-point versions of the single radial immunodiffusion method for quantitating human serum immunoglobulins. Statistical analysis of the results indicated that the results were not normally distributed but that the log normal distribution gives the best fit of any of the well-known frequency distributions. Consequently, statistical analysis of immunoglobulin results must be log transformed before parametric statistical tests can be appropriately applied. In general, there were no significant differences in level, precision, or interlaboratory comparability for these two methods. However, levels were different for participants using Hyland reagents, and better interlaboratory comparability was achieved by the end-point assay for immunoglobulin M. There were no significant differences in reported levels when compared by manufacturer within the same method.
机译:能力验证的结果用于比较单一径向免疫扩散法定量人血清免疫球蛋白的动力学和终点版本。结果的统计分析表明,结果不是正态分布的,但对数正态分布给出了任何众所周知的频率分布的最佳拟合。因此,对免疫球蛋白结果的统计分析必须进行对数转换,然后才能适当地应用参数统计测试。通常,这两种方法在水平,精度或实验室间可比性方面没有显着差异。但是,使用Hyland试剂的参与者的水平有所不同,并且通过免疫球蛋白M的终点检测获得了更好的实验室间可比性。当使用相同方法与制造商进行比较时,报告的水平没有显着差异。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号