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首页> 外文期刊>Journal of Clinical Microbiology >Virulence-associated plasmids in Rhodococcus equi.
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Virulence-associated plasmids in Rhodococcus equi.

机译:马红球菌中与毒力有关的质粒。

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Twenty-three strains of Rhodococcus equi from independent clinical cases were analyzed for the presence of virulence plasmid DNA. Of the clinical isolates, 19 contained an 85-kb plasmid and the remaining 4 contained a 90-kb plasmid. All of the isolates expressed 15- to 17-kDa antigens and were virulent in mice. Restriction enzyme and Southern blot analyses showed large regions of DNA homology between the 85- and 90-kb virulence plasmids. It was concluded tentatively that there are at least two virulence plasmids in R. equi and that they have a common origin.
机译:分析了来自独立临床病例的二十三株马红球菌菌株的毒力质粒DNA。在临床分离株中,有19个包含85 kb质粒,其余4个包含90 kb质粒。所有分离株均表达15至17 kDa抗原,并在小鼠中具有毒性。限制性酶和Southern印迹分析显示85-和90-kb毒力质粒之间的DNA同源性大区域。初步得出结论,马蹄疫杆菌中至少有两种毒力质粒,它们具有共同的起源。

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