Marked Differences in Quantity of Infectious Human Immunodeficiency Virus Type 1 Detected in Persons with Controlled Plasma Viremia by a Simple Enhanced Culture Method

Cécile L. Tremblay; Fran?oise Giguel; Debra P. Merrill; Johnson T. Wong; Eric Rosenberg; Spyros Kalams; Bruce D. Walker; Richard T. DAquila; Martin S. Hirsch

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Marked Differences in Quantity of Infectious Human Immunodeficiency Virus Type 1 Detected in Persons with Controlled Plasma Viremia by a Simple Enhanced Culture Method

机译：通过简单的增强培养方法在控制性血浆病毒血症患者中检测到的1型传染性人类免疫缺陷病毒数量存在明显差异

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Culture of autologous CD4 lymphocytes from peripheral blood mononuclear cells compared favorably with two other methods for the measurement of cell-associated human immunodeficiency virus type 1 (HIV-1). For subjects with undetectable HIV-1 RNA levels in plasma, there was a 10,000-fold range of cell-associated virus detected. This method provides a simple and reproducible means for monitoring cell-associated HIV-1.

机译：与其他两种用于测量细胞相关的人类免疫缺陷病毒1型（HIV-1）的方法相比，从外周血单个核细胞培养的自体CD4淋巴细胞的培养效果优越。对于血浆中检测不到HIV-1 RNA水平的受试者，检测到的细胞相关病毒范围为10,000倍。该方法提供了一种简单且可重现的方法来监测与细胞相关的HIV-1。

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《Journal of Clinical Microbiology》 |2000年第11期|共3页
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Cécile L. Tremblay; Fran?oise Giguel; Debra P. Merrill; Johnson T. Wong; Eric Rosenberg; Spyros Kalams; Bruce D. Walker; Richard T. DAquila; Martin S. Hirsch;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Optimization of quantitative culture assay for human immunodeficiency virus from plasma. Plasma Viremia Group Laboratories of the AIDS Clinical Trials Group (National Institute of Allergy and Infectious Diseases). [J] . J L Lathey, S A Fiscus, S Rasheed, Journal of Clinical Microbiology . 1994,第12期

机译：血浆中人免疫缺陷病毒定量培养测定的优化。艾滋病临床试验小组（国家过敏和传染病研究所）的血浆病毒血症小组实验室。
2. HIGH FREQUENCY OF STOP CODONS IN THE HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE GENE FRAME IN HUMAN IMMUNODEFICIENCY VIRUS+ INDIVIDUALS WITH BELOW DETECTABLE LEVELS OF PLASMA VIREMIA DURING HIGHLY ACTIVE ANTIRETROVIRAL THERAPY [J] . Magdalena Czubala, Kabo Matlho, Maria Arriaga, American journal of infectious diseases . 2012,第3期

机译：在高活性抗病毒治疗期间，人免疫缺陷病毒+个体中具有较低可检测血浆病毒水平的人免疫缺陷病毒-1蛋白酶基因框架中的高终止密码子频率
3. HIGH FREQUENCY OF STOP CODONS IN THE HUMAN IMMUNODEFICIENCY VIRUS?1 PROTEASE GENE FRAME IN HUMAN IMMUNODEFICIENCY VIRUS+ INDIVIDUALS WITH BELOW DETECTABLE LEVELS OF PLASMA VIREMIA DURING HIGHLY ACTIVE ANTIRETROVIRAL THERAPY [J] . Magdalena Czubala, Kabo Matlho, Maria Arriaga, American journal of infectious diseases. . 2012,第3期

机译：在高活性抗病毒治疗期间，人免疫缺陷病毒+个体中人免疫缺陷病毒+个体的蛋白酶基因终止框频率很高。
4. Rapid and Simple Procedure to Detect the Presence of Viruses and Mycoplasma in Cell Cultures used in the Manufacture of Biotherapeutics - (PPT) [C] . Kathleen Souza International Conference: Sample Prep East . 2014

机译：快速简单的程序，以检测生物治疗剂制造中使用的细胞培养物中病毒和支原体的存在 - （PPT）
5. Molecular analysis of the human immunodeficiency virus type-1 reverse transcriptase in infectious virus. [D] . Mulky, Alok Mohan. 2005

机译：传染性病毒中人类免疫缺陷病毒1型逆转录酶的分子分析。
6. Note: Marked Differences in Quantity of Infectious Human Immunodeficiency Virus Type 1 Detected in Persons with Controlled Plasma Viremia by a Simple Enhanced Culture Method [O] . Cécile L. Tremblay, Françoise Giguel, Debra P. Merrill, 2000

机译：注意：通过简单的增强培养方法在控制性血浆病毒血症患者中检测到的1型传染性人类免疫缺陷病毒数量存在明显差异。
7. Optimization of quantitative culture assay for human immunodeficiency virus from plasma. Plasma Viremia Group Laboratories of the AIDS Clinical Trials Group (National Institute of Allergy and Infectious Diseases) [O] . J L Lathey, S A Fiscus, S Rasheed, 1994

机译：血浆中人免疫缺陷病毒的定量培养测定优化。硫血症患者艾滋病临床试验集团（国家过敏和传染病研究所）
8. USPHS/IDSA Guidelines for the Prevention of Opportunistic Infections in Persons211 Infected with Human Immunodeficiency Virus, 1999. U.S. Public Health Service 211 (USPHS) and Infectious Diseases Society of America (IDSA). Morbidity and 211 Mortality Week [R] . Kaplan, J. E., Masur, H., Holmes, K. K. 1999

机译：UspHs / IDsa 1999年人类免疫缺陷病毒感染者预防机会性感染指南。美国公共卫生服务211（UspHs）和美国传染病学会（IDsa）。发病率和211死亡率周

Marked Differences in Quantity of Infectious Human Immunodeficiency Virus Type 1 Detected in Persons with Controlled Plasma Viremia by a Simple Enhanced Culture Method

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