Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex.

T J Hellyer; L E DesJardin; M K Assaf; J H Bates; M D Cave; K D Eisenach

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Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex.

机译：基于IS6110的结核分枝杆菌复合物扩增试验的特异性。

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The specificity of IS6110 for the Mycobacterium tuberculosis complex has recently been questioned. We observed no cross-reaction with 27 nontuberculous mycobacteria using strand displacement- and PCR-based amplification of the nucleotide 970 to 1026 and 762 to 865 regions of IS6110. These data support use of selected regions of IS6110 as M. tuberculosis complex-specific targets.

机译：IS6110对结核分枝杆菌复合物的特异性最近受到质疑。我们使用IS6110核苷酸970至1026和762至865区域的基于链置换和PCR的扩增，未观察到与27种非结核分枝杆菌的交叉反应。这些数据支持将IS6110的选定区域用作结核分枝杆菌复合物特异性靶标。

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《Journal of Clinical Microbiology》 |1996年第11期|共4页
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T J Hellyer; L E DesJardin; M K Assaf; J H Bates; M D Cave; K D Eisenach;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Comparison of Two Nucleic Acid Amplification Assays, the Xpert MTB/RIF Assay and the Amplified Mycobacterium Tuberculosis Direct Assay, for Detection of Mycobacterium tuberculosis in Respiratory and Nonrespiratory Specimens [J] . Jeanette Teo, Roland Jureen, Donald Chiang, Journal of Clinical Microbiology . 2011,第10期

机译：比较两种用于检测呼吸道和非呼吸道标本中的结核分枝杆菌的核酸扩增检测法，Xpert MTB / RIF检测法和扩增的结核分枝杆菌直接检测法
2. Comparison of Two Nucleic Acid Amplification Assays, the Xpert MTB/RIF Assay and the Amplified Mycobacterium Tuberculosis Direct Assay, for Detection of Mycobacterium tuberculosis in Respiratory and Nonrespiratory Specimens [J] . Jeanette Teo, Roland Jureen, Donald Chiang, Journal of Clinical Microbiology . 2011,第10期

机译：比较两种用于检测呼吸道和非呼吸道标本中的结核分枝杆菌的核酸扩增检测法，Xpert MTB / RIF检测法和扩增的结核分枝杆菌直接检测法
3. Clinical value of IS6110-based loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis complex in respiratory specimens [J] . AryanE., MakvandiM., FarajzadehA., Journal of Infection . 2013,第6期

机译：基于IS6110的环介导等温扩增在呼吸道标本中检测结核分枝杆菌复合物的临床价值
4. Mycobacterium tuberculosis Antigen-Specific IL-2R and IP-10 Expression Changes in Chronic Obstructive Pulmonary Disease Patients with in Latent Tuberculosis Infection [C] . Sungyong Bong, Sunghyun Kim, Joo Hwan Hwang, International Molecular Medicine Tri-Conference. . 2016

机译：结核分枝杆菌抗原特异性IL-2R和IP-10表达变化慢性阻塞性肺病患者潜在结核病感染
5. Type I Interferon Induction by Diverse Strains of the Mycobacterium Tuberculosis Complex. [D] . Wiens, Kirsten E. 2017

机译：不同菌株结核分枝杆菌复合物的I型干扰素诱导。
6. Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex. [O] . S H Gillespie, T D McHugh, L E Newport 1997

机译：基于IS6110的结核分枝杆菌复合物扩增试验的特异性。
7. Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex [O] . T J Hellyer, L E DesJardin, M K Assaf, 1996

机译：基于IS6110的分枝杆菌复合物的扩增测定的特异性

Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex.

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