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首页> 外文期刊>Journal of Clinical Microbiology >Pneumococcal resistance to antimicrobial agents in the province of Québec, Canada.
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Pneumococcal resistance to antimicrobial agents in the province of Québec, Canada.

机译：加拿大魁北克省的肺炎球菌对抗菌剂的耐药性。

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摘要

The serogroup/serotypes (SGTs) and antimicrobial susceptibilities to 10 antimicrobial agents of 110 clinical strains of Streptococcus pneumoniae were determined. Strains intermediately resistant or highly resistant to penicillin G (80 of 110) belonged predominantly to SGTs 23 (45.0%), 19 (13.7%), 6 (10.0%), 9 (6.2%), and 14 (3.7%). The MICs of all cephalosporins, tetracycline, trimethoprim-sulfamethoxazole, and chloramphenicol increased along with the MICs of penicillin G. However, erythromycin resistance and clindamycin resistance were observed more frequently among the intermediately penicillin-resistant strains. Multiple resistance was observed for 32 strains, of which 25 were highly resistant to penicillin G and belong to SGT 23F. All strains were susceptible to vancomycin.
机译：确定了110株肺炎链球菌临床菌株的血清群/血清型（SGT）和对10种抗菌剂的敏感性。对青霉素G有中等抵抗力或高度抵抗力的菌株主要属于SGTs 23（45.0％），19（13.7％），6（10.0％），9（6.2％）和14（3.7％）。所有头孢菌素，四环素，甲氧苄啶-磺胺甲恶唑和氯霉素的MIC随青霉素G的MIC的增加而增加。但是，在中等耐青霉素的菌株中，红霉素耐药性和克林霉素耐药性的发生率更高。对32个菌株观察到多重抗性，其中25个对青霉素G具有高度抗性并且属于SGT 23F。所有菌株均对万古霉素敏感。

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