...
首页> 外文期刊>Journal of Clinical Microbiology >Clonal Spread of Pediatric Isolates of Ciprofloxacin-Resistant, emm Type 6 Streptococcus pyogenes
【24h】

Clonal Spread of Pediatric Isolates of Ciprofloxacin-Resistant, emm Type 6 Streptococcus pyogenes

机译:耐环丙沙星的化脓性链球菌6型链球菌儿科分离株的克隆传播

获取原文
           

摘要

Twenty-four community isolates of Streptococcus pyogenes resistant to ciprofloxacin and susceptible to levofloxacin, gatifloxacin, and moxifloxacin were studied. Sequence determination of the quinolone resistance-determining regions in the gyrA and parC genes revealed a T/G mutation in parC leading to a Ser79Ala substitution in ParC. All isolates were of the emm type 6, and 18 and 2 of them were indistinguishable or closely related, respectively, on the basis of pulsed-field gel electrophoresis.
机译:研究了二十四个化脓性链球菌的社区分离株,它们对环丙沙星具有耐药性,并对左氧氟沙星,加替沙星和莫西沙星敏感。对 gyrA parC 基因中喹诺酮耐药性决定区的序列测定揭示了 parC 中的T / G突变,导致Ser79Ala取代。 ParC。在脉冲场凝胶电泳的基础上,所有分离株均为 emmm 类型6,其中18和2分别没有区别或密切相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号