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首页> 外文期刊>Journal of Clinical Microbiology >Pandemic Serovars (O3:K6 and O4:K68) of Vibrio parahaemolyticus Associated with Diarrhea in Mozambique: Spread of the Pandemic into the African Continent
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Pandemic Serovars (O3:K6 and O4:K68) of Vibrio parahaemolyticus Associated with Diarrhea in Mozambique: Spread of the Pandemic into the African Continent

机译：莫拉比克副溶血性弧菌大肠炎（O3：K6和O4：K68）与腹泻相关：大流行病蔓延到非洲大陆

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摘要

Forty-two episodes of Vibrio parahaemolyticus infections were detected in Beira, Mozambique, from January to May 2004. The majority of the isolates (81%) belonged to the pandemic serovars (O3:K6 and O4:K68) of V. parahaemolyticus. The pandemic serovars were positive by group-specific PCR (GS-PCR) and a PCR specific for open reading frame ORF8 (ORF8-PCR), which are molecular markers of the pandemic clone, and were positive for tdh but negative for trh. The remaining 19% of the strains also possessed the tdh gene but were GS-PCR and ORF8-PCR negative and did not belong to the pandemic serovars. Patients with V. parahaemolyticus infection were older (mean age, 27 years) than patients infected by other diarrheal agents (mean age, 21 years). Ten percent of diarrhea patients from whom no V. parahaemolyticus was cultured were severely dehydrated, but none of the V. parahaemolyticus cases were severely dehydrated. This is the first report of the isolation of pandemic strains of V. parahaemolyticus in sub-Saharan Africa and clearly indicates that the pandemic of V. parahaemolyticus has spread into the African continent.
机译：2004年1月至2004年5月在莫桑比克贝拉检测到42次副溶血性弧菌感染。大多数分离株（81％）属于大流行性血清型（O3：K6和O4：K68）。 ）的 V。副溶血。通过组特异性PCR（GS-PCR）和针对开放阅读框ORF8的PCR（ORF8-PCR），大流行性血清型呈阳性，这是大流行性克隆的分子标记，而对 tdh 呈阳性>，但对 trh 不利。其余19％的菌株也具有 tdh 基因，但GS-PCR和ORF8-PCR阴性，不属于大流行性血清型。患有 V的患者。溶血副溶血性感染的年龄（平均年龄为27岁）比其他腹泻病患者的平均年龄（21岁）高。百分之十的腹泻患者没有V。副溶血性的培养被严重脱水，但 V均无。副溶血性病例严重脱水。这是分离出 V大流行毒株的第一份报告。撒哈拉以南非洲的parahaemolyticus 清楚地表明 V大流行。 parahaemolyticus 已经传播到非洲大陆。

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