Invasive Pneumococcal Infection in a Healthy Infant Caused by Two Different Serotypes

Ana Lucia S. Sgambatti de Andrade; Fabiana Cristina Pimenta; Cristina Aparecida Borges Laval; Jo?o Guimar?es de Andrade; Maria Luiza Guerra; Maria Cristina C. Brandileone

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Invasive Pneumococcal Infection in a Healthy Infant Caused by Two Different Serotypes

机译：由两种不同血清型引起的健康婴儿的侵袭性肺炎球菌感染。

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We present a case of invasive pneumococcal infection in a healthy 10-month-old infant from whom Streptococcus pneumoniae serotype 23F was isolated from the blood and serotype 23B was isolated from the cerebrospinal fluid. Both serotypes were penicillin nonsusceptible. Pulsed-field gel electrophoresis analysis demonstrated that the two serotypes had distinct DNA patterns, indicating that infection did not occur as a result of capsular transformation but as a result of a mixed infection with two distinct pneumococcal serotypes.

机译：我们提出了一个健康的10个月大婴儿的侵袭性肺炎球菌感染的病例，从血液中分离出肺炎链球菌血清型23F，从脑脊液中分离出血清型23B。两种血清型均为不敏感的青霉素。脉冲场凝胶电泳分析表明，两种血清型具有不同的DNA模式，表明感染不是由于荚膜转化而发生，而是由于两种不同的肺炎球菌血清型混合感染而发生的。 展开▼

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《Journal of Clinical Microbiology》 |2004年第5期|共2页

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Ana Lucia S. Sgambatti de Andrade; Fabiana Cristina Pimenta; Cristina Aparecida Borges Laval; Jo?o Guimar?es de Andrade; Maria Luiza Guerra; Maria Cristina C. Brandileone;
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中图分类医学微生物学（病原细菌学、病原微生物学）;

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1. Serum samples from infants vaccinated with a pneumococcal conjugate vaccine, PncT, protect mice against invasive infection caused by Streptococcus pneumoniae serotypes 6A and 6B. [J] . Saeland E, Jakobsen H, Ingolfsdottir G, The Journal of Infectious Diseases . 2001,第2期

机译：接种了肺炎球菌结合疫苗PncT的婴儿的血清样本可保护小鼠免受由肺炎链球菌血清型6A和6B引起的侵袭性感染。

2. Serotype 19A Is the most common serotype causing invasive pneumococcal infections in children. [J] . Kaplan SL, Barson WJ, Lin PL, Pediatrics: Official Publication of the American Academy of Pediatrics . 2010,第3期

机译：血清型19A是引起儿童侵袭性肺炎球菌感染的最常见血清型。

3. Comparison of invasive pneumococcal disease caused by serotype 19A and non-19A pneumococci in children: More empyema in serotype 19A invasive pneumococcal disease [J] . LaiC.-Y., HuangL.-M., LeeP.-Y., Journal of microbiology, immunology, and infection: Wei mian yu gan ran za zhi . 2014,第1期

机译：儿童血清型19A和非19A肺炎球菌引起的侵袭性肺炎球菌疾病的比较：血清型19A侵袭性肺炎球菌疾病引起的更多脓胸

4. A Retrospective Cohort Study on the Invasive Fungal Infection in the Preterm Infants [C] . Dan Dang, Xin Mu, Jian Tang, International Conference on Applied Mathematics, Modelling and Statistics Application . 2018

机译：早产儿侵袭性真菌感染的回顾性队列研究

5. Dynamics of dengue antibodies: Transplacental transfer, decline after birth and the serotype specific response to infection among infants and children in Thailand. [D] . van Panhuis, Willem G. 2009

机译：登革热抗体的动力学：泰国婴儿和儿童中胎盘转移，出生后下降和血清型特异性感染反应。

6. Invasive Pneumococcal Infection in a Healthy Infant Caused by Two Different Serotypes [O] . Ana Lucia S. Sgambatti de Andrade, Fabiana Cristina Pimenta, Cristina Aparecida Borges Laval, 2004

机译：由两种不同血清型引起的健康婴儿的侵袭性肺炎球菌感染。

7. Invasive Pneumococcal Infection in a Healthy Infant Caused by Two Different Serotypes [O] . de Andrade, Ana Lucia S. Sgambatti, Pimenta, Fabiana Cristina, Laval, Cristina Aparecida Borges, 2004

机译：由两种不同血清型引起的健康婴儿的侵袭性肺炎球菌感染。

8. Importance of the K1 Capsule in Invasive Infections Caused by Escherichia coli [R] . Cross, A. S., Gemski, P., Sadoff, J. C., 1984

机译：K1胶囊在大肠埃希菌引起的侵袭性感染中的重要性

1. 儿童侵袭性肺炎链球菌感染的血清型和耐药性 [J] . 吕志勇 ,姚开虎 ,宋文琪 . 中国感染控制杂志 . 2021,第007期

2. 广州低龄婴儿侵袭性B族链球菌血清型分布 [J] . 关小珊 ,雷娟梅 ,钟华敏 . 国际检验医学杂志 . 2019,第006期

3. 102株侵袭性肺炎链球菌血清型分布特征及耐药谱分析 [J] . 任红宇 ,王艳晴 ,李一楠 . 中国人兽共患病学报 . 2021,第009期

4. 深圳地区儿童侵袭性肺炎链球菌病的临床特点及分离株耐药性和血清型分析 [J] . 谭锟 ,王红梅 ,鲍燕敏 . 中华实用儿科临床杂志 . 2020,第008期

5. 深圳地区儿童侵袭性肺炎链球菌病的临床特点及分离株耐药性和血清型分析 [J] . 谭锟 ,王红梅 ,鲍燕敏 . 中华实用儿科临床杂志 . 2020,第008期

6. 新生儿侵袭性B族溶血链球菌感染血清型与临床表现相关性及药敏结果分析研究 [C] . LI li ,李丽 ,WU Weiyuan . 2017*杭州*整合急救医学大会、2017年第32届全国危重病急救医学学术会议、江浙沪中医急症/中西医结合危重病急救医学学术会议、第八届浙江省立同德医院国际学术周中西医结合急救论坛 . -1

7. 5岁以下儿童侵袭性肺炎链球菌病的血清型及耐药性分析 [A] . 王铮 . 2015

1. 一种引起坏死性筋膜炎的变异A族侵袭性链球菌的检测方法 [P] . 中国专利： CN1884576A . 2006-12-27

2. 丹酚酸A在制备治疗耐甲氧西林金黄色葡萄球菌感染性肺炎药物中的应用 [P] . 中国专利： CN111053764B . 2021.05.07

3. immunogenic composition for infants, vaccine, process for producing the vaccine, use of the immunogenic composition or vaccine, and method for preventing an elderly human host from having a pneumococcal disease caused by streptococcus pneumoniae serotype 22f infection [P] . 外国专利： BRPI0620460A2 . 2011-11-16

机译：婴儿免疫原性组合物，疫苗，疫苗的生产方法，免疫原性组合物或疫苗的用途以及防止老年人宿主患有由肺炎链球菌血清型22f感染引起的肺炎球菌疾病的方法

4. Viniferin derivatives, preparation method thereof and composition for preventing or treating infection caused by pneumococcal biofilm comprising the same as an active ingredient [P] . 外国专利： KR20210041662A . 2021-04-16

机译：Viniferin衍生物，其制备方法和组合物用于预防或治疗由包含与活性成分相同的肺炎球菌生物膜引起的感染

5. Urine based detection of a disease state caused by a pneumococcal infection [P] . 外国专利： US8685739B2 . 2014-04-01

机译：基于尿液的肺炎球菌感染引起的疾病状态检测

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Invasive Pneumococcal Infection in a Healthy Infant Caused by Two Different Serotypes

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