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首页> 外文期刊>Journal of Clinical Microbiology >Clinical and Epidemiological Aspects of Infections Caused by Fusarium Species: a Collaborative Study from Israel
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Clinical and Epidemiological Aspects of Infections Caused by Fusarium Species: a Collaborative Study from Israel

机译：镰刀菌属物种引起的感染的临床和流行病学方面：来自以色列的合作研究

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摘要

Fusarium infections are an important problem worldwide, commonly affecting immunocompromised individuals. We conducted a retrospective study in two Israeli tertiary medical centers of factors predisposing to infection by Fusarium spp. and their influence on the epidemiology and clinical outcome of this infection. Fusarium spp. were isolated from 89 patients with a median age of 57 years. Sixty-eight patients were considered immunocompetent. Seven patients had disseminated disease, 34 had locally invasive disease, and 48 had superficial infection. Most infections were limited and occurred mainly in lower limbs. Factors associated with in-hospital mortality were chronic renal failure, hematological malignancy, immunosuppression, disseminated infection, and positive blood culture. Multivariate analysis showed that chronic renal failure, hematological malignancy, burns, and disseminated infection were independently associated with mortality. A surge in the frequency of infections was noticed during the summer for patients from rural areas, involving mainly the eyes and lungs. At one of the hospitals (in a mountainous area), there was an increase in the isolation rate over time.
机译： Fusarium 感染是世界范围内的重要问题，通常会影响免疫功能低下的人。我们在以色列的两个三级医疗中心进行了一项回顾性研究，研究了易受 Fusarium spp感染的因素。及其对这种感染的流行病学和临床结果的影响。 Fusarium spp。分离自89位中位年龄为57岁的患者。 68名患者被认为具有免疫能力。七名患者传播疾病，三十四名患有局部浸润性疾病，四十八名患有浅表感染。大多数感染是有限的，主要发生在下肢。与院内死亡率相关的因素是慢性肾衰竭，血液系统恶性肿瘤，免疫抑制，弥散性感染和血液培养阳性。多因素分析表明，慢性肾功能衰竭，血液系统恶性肿瘤，烧伤和传播感染与死亡率独立相关。夏季，农村地区（主要是眼睛和肺部）的患者发现感染频率激增。在其中一所医院（在山区），隔离率随时间增加。

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