Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard

Torbj?rn Norén; Ingeg?rd Alriksson; Josefin Andersson; Thomas ?kerlund; Magnus Unemo

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Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard

机译：艰难梭菌检测的快速灵敏的环介导等温扩增试验挑战了细胞毒素B细胞试验和培养作为金标准

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Compared to the composite gold standard cytotoxin B assay and toxigenic culture, the loop-mediated isothermal amplification (LAMP) test for Clostridium difficile had a sensitivity and specificity of 98%, positive predictive value of 92%, and negative predictive value of >99%. A one-hour turnaround time for the LAMP test provides rapid diagnosis and cost savings.

机译：与复合金标准细胞毒素B测定法和产毒培养物相比，艰难梭菌的环介导等温扩增（LAMP）试验的敏感性和特异性为98％，阳性预测值为92％，阴性预测值为> 99％。 LAMP测试的一小时周转时间可以快速诊断并节省成本。

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《Journal of Clinical Microbiology》 |2011年第2期|共2页
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Torbj?rn Norén; Ingeg?rd Alriksson; Josefin Andersson; Thomas ?kerlund; Magnus Unemo;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard [J] . Torbj?rn Norén, Ingeg?rd Alriksson, Josefin Andersson, Journal of Clinical Microbiology . 2011,第2期

机译：艰难梭菌检测的快速灵敏的环介导等温扩增试验挑战了细胞毒素B细胞试验和培养作为金标准
2. Sensitive and Rapid Detection of ermB Gene in Clostridium difficile by Loop-Mediated Isothermal Amplification [J] . Lin Minyi, Liu Wei, Wang Pu, The American Journal of Gastroenterology . 2014,第Suppla2期

机译：回路介导的等温扩增灵敏快速检测艰难梭菌中的ermB基因
3. Application of isothermal helicase-dependent amplification with a disposable detection device in a simple sensitive stool test for toxigenic Clostridium difficile. [J] . Chow WH, McCloskey C, Tong Y, The Journal of molecular diagnostics: JMD . 2008,第5期

机译：等温解旋酶依赖性扩增与一次性检测装置在产毒性艰难梭菌的简单敏感粪便检测中的应用。
4. A sensitive and rapid detection of Escherichia coli O157 in raw milk by loop-mediated isothermal amplification combined with 4-(2-pyridylazo) resorcinol monosodium salt [C] . Deguo Wang, Yongzhen Wang, Fugang Xiao, International Conference on Medical Engineering and Bioinformatics . 2015

机译：通过环介导的等温扩增与4-（2-吡啶基氮杂）间苯二酚单钠盐组合的原料乳中大肠杆菌O157的敏感和快速检测
5. Integration of Microfluidic Chip with Loop-mediated Isothermal Amplification (LAMP) Assay for Rapid Quantification of Enterococcus Faecalis [D] . Han, Muyue. 2018

机译：微流体芯片与环介导等温扩增（灯）测定的集成，用于快速定量肠球菌粪便
6. Notes: Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard [O] . Torbjörn Norén, Ingegärd Alriksson, Josefin Andersson, 2011

机译：注释：用于艰难梭菌检测的快速灵敏的环介导等温扩增试验挑战了细胞毒素B细胞试验和培养作为金标准
7. Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard▿ [O] . Norén, Torbjörn, Alriksson, Ingegärd, Andersson, Josefin, 2010

机译：艰难梭菌检测的快速灵敏环介导等温扩增试验挑战了细胞毒素B细胞试验和培养作为金标准▿

Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard

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