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首页> 外文期刊>Journal of Clinical Microbiology >Correlation of Leukorrhea and Trichomonas vaginalis Infection
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Correlation of Leukorrhea and Trichomonas vaginalis Infection

机译：白带和阴道毛滴虫感染的相关性

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Trichomonas vaginalis is a common sexually transmitted infection (STI) causing vaginitis. Microscopy has poor sensitivity but is used for diagnosis of trichomoniasis in resource-poor settings. We aimed to provide a more reliable diagnosis of trichomoniasis by investigating an association with leukorrhea. Women presenting for evaluation of vaginal discharge, STI exposure, or preventative gynecologic examination were evaluated for Trichomonas infection. Vaginal pH was determined and microscopy was performed by the provider, who recorded the number of polymorphonuclear leukocytes (PMNLs) per epithelial cell and the presence of clue cells, yeast, and/or motile trichomonads. Leukorrhea was defined as greater than one PMNL per epithelial cell. Culture and a nucleic acid amplification test (NAAT) were used to detect T. vaginalis. Patients were evaluated for Chlamydia trachomatis and Neisseria gonorrhoeae using NAATs and bacterial vaginosis using Gram stains. Two hundred ninety-four women were enrolled, and 16% were found to have Trichomonas (46/294). Trichomonas infection was more common in parous non-Hispanic, black women, who reported low rates of contraceptive use (33% versus 17%; P = 0.02) and a STI history (85% versus 55%; P = 0.002). These women were more likely to report vaginal discharge (76% versus 59%; P = 0.02) and have an elevated vaginal pH (87% versus 48%; P < 0.001) and gonorrhea infection (15% versus 4%; P = 0.002). Leukorrhea was associated with a 4-fold-increased risk of Trichomonas infection. Leukorrhea on microscopy was associated with Trichomonas vaginitis. Patients with leukorrhea should be evaluated with more-sensitive tests for T. vaginalis, preferably NAATs, if microscopy is negative.
机译：阴道毛滴虫是引起阴道炎的常见性传播感染（STI）。显微镜灵敏度差，但可用于资源贫乏地区的滴虫病诊断。我们旨在通过调查与白带的相关性，为滴虫病提供更可靠的诊断。对评估阴道分泌物，性传播感染或预防性妇科检查的妇女进行滴虫感染评估。确定阴道pH并由提供者进行显微镜检查，该提供者记录每个上皮细胞的多形核白细胞（PMNL）的数量以及线索细胞，酵母和/或运动性滴虫的存在。白带被定义为每个上皮细胞大于一个PMNL。培养物和核酸扩增试验（NAAT）用于检测阴道锥虫。使用NAAT对患者的沙眼衣原体和淋病奈瑟菌进行评估，并使用革兰氏染色对患者的阴道细菌病进行评估。 294名女性入组，其中16％被发现患有滴虫（46/294）。滴虫感染在非西班牙裔黑人女性中更为普遍，她们的避孕药具使用率较低（33％比17％; P = 0.02）和性病史（85％比55％; P = 0.002）。这些女性更容易报告白带（76％比59％; P = 0.02），阴道pH升高（87％比48％; P <0.001） ）和淋病感染（15％对4％; P = 0.002）。白带与滴虫感染风险增加4倍有关。显微镜下白带与滴虫性阴道炎有关。如果显微镜检查呈阴性，则应该对白带患者进行更敏感的阴道锥虫检测，最好是NAAT。

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