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首页> 外文期刊>Journal of Clinical Microbiology >Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae Testing Susceptible to Cefepime by Reference Methods
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Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae Testing Susceptible to Cefepime by Reference Methods

机译:肺炎克雷伯菌产碳青霉烯酶的产肠杆菌科细菌通过参考方法检测对头孢吡肟敏感

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摘要

β-Lactam susceptibility of 499 Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, determined by reference broth microdilution, demonstrated that 14.4% of isolates were categorized as cefepime susceptible according to current CLSI breakpoints. Ceftazidime- and meropenem-susceptible isolates were also observed (2.6 and 3.0%, respectively). Cefepime-susceptible KPC-producing isolates may confuse laboratory staff and clinicians in their therapeutic choices.
机译:通过参考肉汤微稀释法测定的产生499例肺炎克雷伯菌肺炎克雷伯菌酶(KPC)的肠杆菌科细菌对β-内酰胺的敏感性表明,根据当前的CLSI临界点,有14.4%的分离株被归类为头孢吡肟敏感。还观察到头孢他啶和美罗培南敏感的分离株(分别为2.6%和3.0%)。产生头孢吡肟的KPC分离株可能会使实验室工作人员和临床医生混淆其治疗选择。

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