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Consolidating and Exploring Antibiotic Resistance Gene Data Resources

机译:巩固和探索抗生素抗性基因数据资源

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The unrestricted use of antibiotics has resulted in rapid acquisition of antibiotic resistance (AR) and spread of multidrug-resistant (MDR) bacterial pathogens. With the advent of next-generation sequencing technologies and their application in understanding MDR pathogen dynamics, it has become imperative to unify AR gene data resources for easy accessibility for researchers. However, due to the absence of a centralized platform for AR gene resources, availability, consistency, and accuracy of information vary considerably across different databases. In this article, we explore existing AR gene data resources in order to make them more visible to the clinical microbiology community, to identify their limitations, and to propose potential solutions.
机译:抗生素的无限制使用已导致快速获得抗生素抗药性(AR)和传播多药耐药性(MDR)细菌病原体。随着下一代测序技术的出现及其在理解MDR病原体动力学中的应用,迫切需要统一AR基因数据资源以方便研究人员访问。但是,由于缺少用于AR基因资源的集中平台,因此在不同数据库之间,信息的可用性,一致性和准确性差异很大。在本文中,我们将探索现有的AR基因数据资源,以使它们对临床微生物学界更具可见性,确定其局限性,并提出潜在的解决方案。

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